Method and composition for preventing conception

Details Method and composition for preventing conception Method and composition for preventing conception

1988-09-29

1991-07-30

Doll, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 2, 514800, 424 88, 530807, A61K 3738

Patent

active

050360477

ABSTRACT:
A method for preventing conception in mammals which includes administering to the mammals a composition containing (1) free LHRH or its analog and (2) an immunogenic conjugate between LHRH or its analog and a carrier protein. Free LHRH or its analog acts to prevent conception in the mammal during the period from administration to about 6 weeks; the immunogenic conjugate acts to prevent conception during the period from about 6 weeks after administration until the LHRH antibodies formed in response to the conjugate are metabolized, generally about 0.5-2 years.

REFERENCES:
patent: 4419347 (1983-12-01), Nester et al.
patent: 4608251 (1986-08-01), Mia
PCT Int. App., 40 pp., Rigby et al., (1988), CA110(25) 226144.
Brit. UK. Pat. App. 8 pp., Morrison et al., CA110(25) 226143a, 1988.
PCT Int. Appl., 43 pp., Tilbrook, CA109(25) 223417m, (1988).
PCT Int. Appl., 19 pp., Brandon, CA110(17) 148783t, 1988.
Thau, Rosemarie B., Luteinizing Hormone-Releasing Hormone (LHRH) and Its Analogs for Contraception in Women: A Review, Contraception, vol. 29, No. 2, pp. 143-162 (1984).

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