Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1984-01-12
1991-04-02
Nucker, Christine
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
424 858, 435 7021, 4351722, 43524027, 935106, 935110, C07K 1528
Patent
active
050048040
ABSTRACT:
Methods and compositions are provided for recombinant DNA production of Factor VIIIC and truncated derivatives therfeof. Based on amino acid sequences, probes are developed for isolating messenger RNA and/or chromosomal DNA encoding for Factor VIIIC. The Factor VIIIC gene in its entirety or encoding for a fragment thereof is then used for expression of Factor VIIIC in a host.
The bacteriophage .lambda.FVIII23D containing the 14.43kb EcoRI fragment was deposited at the A.T.C.C. on Jan. 4, 1984 and given Accession No. 40094.
REFERENCES:
patent: 4361509 (1982-11-01), Zimmerman et al.
patent: 4419446 (1983-12-01), Howley et al.
patent: 4649132 (1987-03-01), Zimmerman et al.
patent: 4657894 (1987-04-01), Zimmerman et al.
Fulcher & Zimmerman, Proc. Natl. Acad. Sci. U.S.A. (1982), 79:1648-1652.
Tuddenham et al., (1979), J. of Lab. Clinical Medicine 93:40-53.
Austen, (1979), British J. Hematology 43:669-674.
Weinstein et al., (1981), Proc. Natl. Acad. Sci., U.S.A., 78:5137-5141.
Kuo et al., Abstracts for IX International Congress of Thrombosis Hemostasis, (Stockholm, Jul. 1983).
Hybritech Data Sheet (Catalogue #0432).
Fulcher et al., (1983), Blood 61:807.
Fass et al., (1982), Blood 59:594.
Ginsburg et al., (1985), Science 228:1401-1406.
Kurachi et al., (1982), Proc. Natl. Acad. Sci., U.S.A., 79:6461-6464.
Maniatis et al., Molecular Cloning: A Laboratory Manual, pp. 224-228 (1982).
Bloom (1983), Nature 303:474-475.
Muller et al., (1981), Blood 58: 1000-1006.
Muller et al., (1982) Chemical Abstracts, vol. 96, No. 5, p. 480 (Abstract No. 33095v).
Maddox (1983), Nature 306:528.
Rotblat et al., (1984), Biological Abstracts 77:4443 (Abstract No. 40713).
Rotblat et al., (1983), J. Lab. Clin. & Med. 101:736-746.
Kaufman et al., (1982), Molecular and Cellular Biology 2:1304-1319.
Fay et al., (1982), Proc. Natl. Acad. Sci. 79:7200-7204.
Choo et al., (1982), Nature 299:178-180.
Chan et al., (1984), Chemical Abstracts, vol. 100, p. 214, (Abstract No. 63605e).
Rotblat et al., (1985), Biochemistry 24:4294-4300.
Toole et al., (1984), Nature 312:342-347.
Vehar et al., (1984), Nature 312:337-342.
Gitschier et al., (1984), Nature 312:326-330.
Wood et al., (1984), Nature 312:330-337.
Kuo George
Masiarz Frank
Truett Martha
Valenzuela Pablo
Nordisk Gentofte
Nucker Christine
LandOfFree
Method and composition for preparation of factor VIIIC does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and composition for preparation of factor VIIIC, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and composition for preparation of factor VIIIC will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-327452