Method and composition for oral administration of N-acetylcystei

Details Method and composition for oral administration of N-acetylcystei Method and composition for oral administration of N-acetylcystei

1990-07-27

1992-01-14

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424451, 424465, 424464, 424466, 424479, 424489, 514855, 514885, A61K 948

Patent

active

050809067

ABSTRACT:
The blood level of orally administered N-acetylcysteine is substantially increased in a mammal when the N-acetylcysteine is administered in combination with tris(hydroxymethyl)aminomethane or a pharmaceutically acceptable salt thereof, in a molar ratio of about 1:0.8 to about l:l.2.

REFERENCES:
patent: 4081534 (1978-03-01), Elion et al.
patent: 4867976 (1989-09-01), Weld et al.
patent: 4877612 (1989-10-01), Berger et al.
patent: 4894225 (1990-01-01), Zimmerman

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