Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1985-07-17
1989-01-10
Wiseman, Thomas G.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
424 858, 424101, 514 2, 4352401, 4352402, 43524021, 436 63, 436171, 436514, 436518, 436821, 436824, G01N 3348, G01N 118, G01N 33559, G01N 3353
Patent
active
047974753
ABSTRACT:
A composition of matter and method for using the composition of matter to isolate various cell elements from a heterogeneous cell suspension in a simple one step procedure. The composition is a monoclonal antibody mixture including complement and a non-toxic density gradient media. The composition provides a negative selection technique in which undesired subpopulation cells are lysed and separated from the desired cell subpopulation. The invention has particular application to isolation of white cell elements.
REFERENCES:
patent: 4192917 (1980-03-01), Zurawski, Jr.
patent: 4361549 (1982-11-01), Kung et al.
patent: 4361550 (1982-11-01), Kung
Grumet et al. Human Immunology vol. 6 pp. 63-73 1983 "A Simplified New Method for HLA-DR Typing Using the TMI Monoclonal antibody".
Mishell et al. Selected Methols in Cellular Immunology pp. 211-212 1980.
Morgan et al. Blood vol. 18 1961 pp. 89-94 "Separation of Platlets from Whole Blood by the Use of Silicone Fluids". Discussion
Pollack et al. Clin Immunol Immunopathol vol. 24(1) 1982 pp. 15-25 "The Functional Study of DR Positive Human Epidermal Langerhans Cells . . . ".
Lundak et al. J. Immunol Methods vol. 28(3-4) 1979 pp. 277-242 "Separation of Functional Subpopulations of Minke and Lymphoid cells . . . ".
Biological Abstracts, vol. 68, No. 7, 1979, p. 4138, abstract No. 41418, Philadelphia, PA, U.S.; J. W. Chiad et al.: "Isolation of Human T Lymphocytes by a Negative Selection Procedure", & Immunol. Commun. 8(1): 49-54, 1979 * Abstract *.
Tissue Antigens, vol. 16, 1980, pp. 317-325, Munksgaard, Copenhagen, DK; T. A. De Kretser et al.: "The Separation of Cell Populations Using Monoclonal Antibodies Attached to Sepharose" p. 317, Abstract; p. 324, Last Paragraph of "Discussion"*.
Biological Abstracts, vol. 61, 1st Feb. 1976, p. 1491, Abstract No. 14367, Philadelphia, PA, U.S.; V. Ghetie et al.: "Cell Separation by Staphylococcal Protein A-Coated Erythrocytes" & Scand. J. Immunol. 4(5/6): 471:477, 1975 * Abstract *.
Chemical Abstracts, vol. 69, No. 9, 26th Aug. 1968, p. 3120, Abstract No. 33491p, Columbus, Ohio, U.S.; H. Pertoft et al.: "Separation of Various Blood Cells in Colloidal Stlicapoly(vinyl-pyrrolidinone) Gradients", & EXP. Cell Res. 1968, 50(2), 355-368 * Abstract *.
El-Awar Nadim
Hardiwidjaja Steven
Loon Jimmy
Terasaki Paul I.
Teskin Robin L.
The Regents of the University of California
Wiseman Thomas G.
LandOfFree
Method and composition for isolating white cell elements does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and composition for isolating white cell elements, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and composition for isolating white cell elements will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2108422