Method and composition for energy source supplementation during

Details Method and composition for energy source supplementation during Method and composition for energy source supplementation during

1994-07-25

1995-05-30

Henley, III, Raymond

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 23, 514557, 514565, A61K 3700, A61K 3170, A61K 3119, A61K 31195

Patent

active

054201071

ABSTRACT:
A supplement containing lactic acid salts and/or polymers, and optionally simple and/or complex carbohydrates, is employed to promote energy supply, fluid and electrolyte balance, blood glucose homeostasis, blood pH buffering and muscle as well as liver glycogen storage during and after strenuous exercise. The disclosed composition takes advantage of the presence of sodium-mediated intestinal lactate and glucose transporters, intestinal conversion of glucose to lactate, hepatic formation of glycogen from lactate, the preferential uptake of lactate for fuel by cardiac and red skeletal muscles, the alkalizing effect of the combustion of lactate to CO.sub.2 and H.sub.2 O and conversion to glucose of glycogen, and the presence of a sarcolemmal (muscle cell membrane) lactate/hydrogen ion (symport) transport protein to provide beneficial nutritional supplementation during exercise and subsequent recovery.

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