Method and composition for controlled release acarbose...

Details Method and composition for controlled release acarbose... Method and composition for controlled release acarbose...

2005-02-01

2005-02-01

Wilson, James O. (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S054000, C514S909000

Reexamination Certificate

active

06849609

ABSTRACT:
The present invention is directed towards a method and composition for controlled release acarbose formulations. The method and composition disclosed herein combine acarbose and a sustained release matrix. The administration of acarbose alone has been shown to be useful in the treatment of diabetes. Although the initial studies conducted herein were conducted with a delayed release formulation that allowed partial sustained release administered to stimulate sustained release, all indicators from the present invention suggest the formulation of acarbose in a sustained release formulation would have heretofore unexpected benefits. In a sustained release formulation, the ingredient(s) would be a shaped dosage unit having a sustained and regular release of acarbose throughout the small intestine where carbohydrates as a simple sugar are absorbed.

REFERENCES:
patent: 4767850 (1988-08-01), Lange et al.
patent: 4904769 (1990-02-01), Rauenbusch
patent: 5643874 (1997-07-01), Bremer et al.
patent: 6130072 (2000-10-01), Beunink et al.
patent: 6309663 (2001-10-01), Patel et al.
patent: 6387361 (2002-05-01), Rosner
Burnham, T.M. and Wickersham, R.M., Acarbose, Drug Facts and Comparisons, 2000, pp., 297-299, Facts and Comparisons, St. Louis, MO.

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