Method and composition for antiviral therapy

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514460, A61K 3170, A61K 3135

Patent

active

061178446

ABSTRACT:
A method of treatment of diseases of viral origin is disclosed. The method comprises oral or parenteral administration of an antiviral amount of a naturally occurring secoiridoid from plants of the family Oleaceae or derivatives thereof. Preferred oral dosage forms include the secoiridoid oleuropein in pure form or as a component of dried plant material of Olea europaea or a dried extract thereof and a pharmaceutically acceptable carrier.

REFERENCES:
patent: 3033877 (1962-05-01), Veer et al.
patent: 3737550 (1973-06-01), Nook et al.
patent: 3786068 (1974-01-01), Kelly
patent: 3793346 (1974-02-01), Kelly
Renis, Antimicro Agent Chemotherapy, 1969 pp. 167-172, 970.
Walter et al Appl Micro vol 26(5) pp 773-76, 1973.
Hirschman, Noter vol 238 Aug. 20, 1972, pp. 277-79, 1972.
"The Bitter Glucoside of the Olive", W.V. Cruess and C. L. Alsberg, J. Am. Chem. Soc. 56:2115-2117 (1934).
Isolation of a Bacterial Inhibitor from Green Olives, Fleming, et al., Applied Microbiology, vol. 18, No. 5, pp856-860 (1969).
"Preparation of Antimicrobial Compounds by Hydrolysis of Oleuropein from Green Olives", Walter et al., Applied Microbiology, vol. 26, No. 5, pp773-776 (1973).
"Antimicrobial Properties of Oleuropein and Products of Its Hydrolysis from Green Olives", Fleming et al., Applied Microbiology, vol. 26, No. 5, pp777-782 (1973).
"In Vitro Antiviral Activity of Calcium Elenolate", Harold Renis, Antimicrobial Agents and Chemotherapy, 1969 (printed 1970) pp. 167-172.
"Inactivation of DNA Polymerases of Murine Leukaemia Viruses by Calcium Elenolate" S. Z. Hirschman, Nature (New Biology), 238: 277-279 (1972).
"Antiviral Activity of Calcium Elenolate on Parainfluenza Infection of Hamsters", M. G. Soret, Antimicrobial Agents and Chemotherapy, 1969 (printed 1970) pp. 160-166.
"Preliminary Safety Studies with Calcium Elenolate, an Antiviral Agent", Elliot et al., Antimicrobial Agents and Chemotherapy, 1969 (printed 1970) pp. 173-176.
"Binding of Eugenol and O-ethoxybenzoic Acid to Bovine Serum Albumin", S. Fujisawa and E. Masuhara, J. Dent. Res., vol. 60, No. 4, pp. 860-864 (1981).
"Pharmacological Analysis of the Iridoid Oleuropein," V. Petkov and P. Manolov, Drug Res., 22(9) pp. 1476-1486 (1972).
"A Multichemical Defense Mechanism of Bitter Olive Olea Europaea (Oleaceae)", Kubo et al. J. of Chemical Ecology, vol. 11, No. 2, pp. 251-263 (1985).
"Secoiridoids from Olea Europaea", Gariboldi, et al., Phytochem. 25(4) pp. 865-869 (1986).
"Inactivation of Myxoviruses by Calcium Elenolate", Harold Renis, Antimicrobial Agents and Chemotherapy, vol. 8, No. 2 pp. 194-199 (1975).
"Conversion of Secologanin into Elenolic Acid and 18-Oxayohimban Alkaloids", R. T. Brown et al, J. of Chem. Soc. Perkin Trans. vol. 1, pp160-162 (1976).
"Mulluscicides from Olive Olea europaea and Their Efficient Isolation by Countercurrent Chromatographies", I. Kubo and A. Matsumoto, J. Agric. Food Chem., vol. 32, No. 3 pp 687-688 (1984).
"HPLC Analysis of Oleuropein and Some Flavonoids in Leaf and Bud of Olea Europaea L.", P. Ficarra and R. Ficarra, IL Farmaco, vol. 46, No. 6, pp. 803-815 (1991).
"A New Secoiridoid from Olive Wastewaters", R. L. Scalzo and M. L. Scarpati, Journal of Natural Products, vol. 56, No. 4, pp. 621-623 (1993).
"Leaf Extract of Olea eropea Rich in Oleuropeine, Products from It, Their Application as Medicines and Compositions Containing Them", G. Combes and A. Escaut, Chem Abstracts, vol. 98: 221797r (1983).
"(--)-Elenolic Acid Esters", Takano et al., Chem Abstracts, vol. 106: 67534c (1987).
"Preparation of Dihydropyran Derivative as Antiviral Agents and Precursors for Alkyl (--)-Elenolates", Takano et al., Chem Abstracts, vol. 113: 58936c (1990).
"Structure and Stereochemistry of Elenolic Acid", MacKellar et al., J. Am. Chem. Soc. vol. 95 (21) pp. 7155-7156 (1973).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method and composition for antiviral therapy does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and composition for antiviral therapy, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and composition for antiviral therapy will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-96174

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.