Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Combination of viral and bacterial antigens
Patent
1993-08-12
1998-03-17
Elliott, George C.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Combination of viral and bacterial antigens
4241841, 4242021, 4242031, 4242121, 4242171, 4242181, 4242191, 4242241, 4242271, 4242281, 4242301, 4242331, 4242341, 4242441, 4242451, 4242461, 4242471, 4242491, 4242541, 4242581, 4242611, A61K 3902, A61K 3912, A61K 39116, A61K 39295
Patent
active
057283850
ABSTRACT:
A method of immunization, and compositions therefor, are provided for substantially preventing or reducing the symptoms of at least one infectious disease and at least one chronic immune mediated disorder. An immunogenic challenge which supplements the normal childhood immunization schedule can help ensure the proper maturation of the immune system and prevent the development of chronic immune mediated disorders.
REFERENCES:
patent: 4152415 (1979-05-01), Harris et al.
patent: 4625015 (1986-11-01), Green et al.
patent: 4695459 (1987-09-01), Lawrence et al.
patent: 4710380 (1987-12-01), Arthur
patent: 4857318 (1989-08-01), Lee
patent: 4894332 (1990-01-01), Schaller et al.
patent: 5151023 (1992-09-01), Kuzuhara et al.
patent: 5254340 (1993-10-01), Van Leengoed et al.
Baraff et al, "Immunologic Response to Early and Routine DTP Immunization in Infants", Pediatrics, 37-42 (Jan. 1984).
Barrett et al, "Multiple Antigen for Immunization Against Poliomyelitis, Diphtheria, Pertussis, and Tetanus" JAMA, 167:1103-1107 (Jun. 28, 1958).
Barrett et al, "Multiple Antigen Immunization of Infants Against Poliomyelitis, Diphtheria, Pertussis, and Tetanus", Pediatrics, pp. 720-736 (Nov. 1962).
Blom, et al., "The Swedish childhood diabetes study: Vaccinations and Infections as risk determinants for diabetes in childhood", Diabetologia, 34:176-181 (1991).
Classen, et al., Evidence That Cyclosporine Treatment During Pregnancy Predisposes Offspring to Develop Autoantibodies, Transplantation, Vol 51, No. 5, pp. 1052-1057, May 1991.
Dengrove et al, IgG and IgG Subclass Specific Antibody Responses to Diphtheria and Tetanus Toxoids in Newborns and Infants Given DTP Immunization, Pediatric Research, Vol. 20 No. 8, pp. 735-739, 1986.
Elias et al, Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein, Natl. Acad. Sci. USA, Vol. 88, pp. 3088-3091, Apr. 1991.
Elias et al, Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein, Proc. Natl. Acad. Sci. USA, Vol. 87, pp. 1576-1580, Feb. 1990.
Fagan McInerney, et al., Prevention of Insulitis and Diabetes Onset by Treatment With Complete Freund's Adjuvant in NOD Mice, Diabetes, Vol. 40, pp. 715-725, Jun. 1991.
General Recommendations on Immunization, JAMA, Vol. 262 No. 1, pp. 22-26, Jul. 7, 1989 (from the CDC).
General Recommendations on Immunization, JAMA, Vol. 262, No 3, pp. 339-340, Jul. 21, 1989 (from the CDC).
Grange et al, BCG vaccination and cancer, Tubercle, Vol. 71, pp. 61-64.
Green et al, Incidence of childhood-onset insulin dependent diabetes mellitus: the Eurodiab Ace study, The Lancet, Vol. 339, pp. 905-909, Apr. 11, 1992.
Halsey et al, The efficacy of DPT and oral poliomyelitis immunization schedules initiated from birth to 12 weeks of age, Bulletin of the World Health Organization, Vol. 63 (6), pp. 1151-1169, 1985.
Harada, et al., Prevention of overt diabetes and insulitis in NOD mice by a single BCG vaccination, Diabetes Research and Clinical Practice, Vol. 8, pp. 85-89, 1990.
Huang et al, Pertussigen Treatment Retards, But Fails To Prevent, The Development of Type I, Insulin-Dependent Diabetes Mellitus (IDDM) In NOD Mice, Autoimmunity, Vol. 9, pp. 311-317, 1991.
Huang et al, The Effect of Pertussis Vaccine on the Insulin-Dependent Diabetes induced by Streptozocin in Mice, Pediatric Research, Vol. 18, No. 2, pp. 221-226, 1984.
Imamura et al, Intrapericardial OK-432 Installation for the Management of Malignant Pericardial Effusion, Cancer, Vol. 68 No. 3, pp. 259-263, Jul. 15, 1991.
John, T. Jacob, Immune response of neonates to oral poliomyelitis vaccine, British Medical Journal, Vol. 289, pp. 881, Oct. 6, 1984.
Kolb et al, Analysis of 22 Immunomodulatory Substances for Efficacy in Low-Dose Streptozotocin-Induced Diabetes, Diabetes Research, Vol. 6, pp. 21-27, 1987.
Krolewski et al, Epidemiologic Approach to The Etiology of Type I Diabetes Mellitus and its Complications, The New England Journal of Medicine, Vol. 317 No. 22, pp. 1390-1398, Nov. 26, 1987.
Madore et al, Safety and Immunologic Response to Haemophilus Influenzae Type b Oligosaccharide-CRM Conjugate Vaccine in 1- to 6-Month-Old Infants, Pediatrics, Vol. 85 No. 3, pp. 331-337, Mar. 1990.
Mukai et al, Combination Therapy of Local Administration of OK-432 and Radiation for Esophageal Cancer, Int. J. Radiation Oncology Biol. Phys., Vol. 22 No. 5, pp. 1047-1050, 1992.
Ogita et al, OK-432 Therapy for Unresectable Lymphangiomas in Children, Journal of Pediatric Surgery, Vol. 26 No. 3, pp. 263-270, Mar. 1991.
Oldstone, et al., Viruses as Therapeutic Agents, J. Exp. Med., Vol. 171, pp. 2091-2100, Jun. 1990.
Oldstone, Michael B.A., Prevention of Type I Diabetes in Nonobese Diabetic Mice by Virus Infection, Science, Vol. 239, pp. 500-502, Jan. 29, 1988.
Pabst et al, Effect of breast-feeding on antibody response to conjugate vaccine, The Lancet, Vol. 336, pp. 269-270, Aug. 4, 1990.
Pearce et al, Studies of Concanavalin A in Nonobese Diabetic Mice. I. Prevention of Insulin-Dependent Diabetes, The Journal of Pharmacology Experimental Therapeutics, Vol. 258 No. 2, pp. 710-715, 1991.
Perkins et al, Serological Response of Infants To Poliomyelitis Vaccine, British Medical Journal, pp. 68-71, Jul. 12, 1958.
Provenzano et al, Immunization and Antibody Response in the Newborn Infant, The New England Journal of Medicine, Vol. 273, No. 18, pp. 959-965, Oct. 28, 1965.
Sadelain, et al., Prevention of Type I Diabetes in NOD Mice by Adjuvant Immunotherapy, Diabetes, Vol. 39, pp. 583-589, May 1990.
Satoh et al, Treatment With Streptococcal Preparation (OK-432) Suppresses Anti-Inlet Autoimmunity and Prevents Diabetes in BB Rats, Diabetes, Vol. 37, pp. 1188-1194, Sep. 1988.
Satoh et al, Recombinant Human Tumor Necrosis Factor.varies.Suppresses Autoimmune Diabetes in Nonobese Diabetic Mice, Rapid Publication, Vol. 84, pp. 1345-1348, Oct. 1989.
Schwimmbeck, et al., Abrogation of Diabetes in BB Rats by Acute Virus Infection, Association of Viral-Lymphocyte Interactions, The Journal of Immunology, Vol. 140, No. 10, pp. 3394-3400, May 15, 1988.
Seino et al, Inhibition of autoimmune diabetes in NOD mice with serum form streptococcal preparation (OK-432)-injected mice, Clin. exp. Immunol., Vol. 86, pp. 413-418, 1991.
Shintani, et al., Mechanism of Action of A Streptococcal Preparation (OK-432) in Prevention of Autoimmune Diabetes in NOD Mice, The Journal of Immunology, Vol. 144, No. 1, pp. 136-141, Jan. 1, 1990.
Simultaneous Administration of Multiple Vaccines, Active Immunization, pp. 16-19.
Spigland et al, Immunization of Infants With Formalinized Poliomyelitis Vaccine (Salk Type), Pediatrics, Vol. 25, pp. 812-821, May 1960.
Toyota et al, Islet Activating Protein (IAP) Derived from the Culture Supernatant Fluid of Bordetella Pertussis: Effect on Spontaneous Diabetic Rats, Diabetologia, Vol. 14, pp. 319-323.
Toyota et al, Streptococcal Preparation (OK-432) Inhibits Development of Type I Diabetes in NOD Mice, Diabetes, Vol. 35, pp. 496-499, April 1986.
Vagede et al., Vaccine Technology, Vol. 23, pp. 628-643.
Wheeley et al, Hepatitis B Vaccine in the Prevention of Perinatally Transmitted Hepatitis B Virus infection: Final Report on a West Midlands Pilot Study, Journal of Medical Virology, Vol. 30, pp. 113-116, 1990.
Herold, Kevan C et at, Prevention of Autoimm. Diab. 2/Nonactivity Anti-CD3 Monoctonal Antibody , Diabetes, Vol. 41, pp. 385-391 infectious Disease Ch. 3 Prevention of Infection pp. 21-24 "Immunization Procedures for Adults", Mar. 1992.
Mihara, Masahiko et at, Autoimmune Kidney Disease in MRL/1Pr Mice Inhibited by OK-132; II. Effect of Indomethacin, J. Pharmacobio-Dyn., 15: 255-259, 1992.
Mihara, M. et al., Autoimmune Kidney Disease in MRL/Mp-Ipr mice inhibited by OK-432, a streptococcal preparation, Clin. exp. Immunol. 78:102-107, 1989.
Guberski, D.L. et at., Induction of Type I Diabetes by Kilham's Rat Virus in Diabetes-Resistant BB/Wor Rats, Science, 25:1010-1013, 15 Nov. 1991.
Luh, Kwen-Tay, et al., Comparison of OK-432 and Mitomycin C Pleurodesis for Malignant Pleural Effusion Caused by Lung Canc
Classen Immunotherapies, Inc.
Cooper Iver P.
Elliott George C.
Railey II Johnny F.
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