Method and combined test elements for detection of heme

Details Method and combined test elements for detection of heme Method and combined test elements for detection of heme

1979-01-15

1981-04-07

Marantz, Sidney

Chemistry: physical processes

Physical processes

Crystallization

23913, 252408, 422 56, 422 61, 435 4, 435 28, 435805, G01N 3352, G01N 3372

Patent

active

042603935

ABSTRACT:
A diagnostic method and indicator for heme in controlled sensitivity is provided by impregnating a bibulous body, such as a test strip with a solution of a color indicator in leuco form and drying and storing in stable active form, and in use applying to the strip a test sample containing heme. The test color is then developed in the strip by wetting the test sample and strip in contact therewith with a peroxide solution of a solvent for the leuco dye carrying the oxygen released from the peroxide by the heme peroxidase in the test sample, such as blood or body tissue or residues containing occult blood whose presence is to be determined.

REFERENCES:
patent: 2838377 (1958-06-01), Fonner
patent: 3996006 (1976-12-01), Pagano
patent: 4175923 (1979-11-01), Friend

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