Method and assay using inactivation of factors Va and VIIIa by a

Details Method and assay using inactivation of factors Va and VIIIa by a Method and assay using inactivation of factors Va and VIIIa by a

1989-08-21

1991-09-24

Hill, Jr., Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving blood clotting factor

422 61, 436 69, 436 86, C12Q 156

Patent

active

050513575

ABSTRACT:
A method and test kit for indirectly assaying for Protein C is described. The method uses tissue thrombomodulin/tissue factor (TTP) and calcium chloride to produce thrombin and activate Protein C to Protein Ca without fibrin formation and then allows time for Protein Ca to inactivate Factors Va and VIIIa. A deficient plasma has a decreased activated thromboplastin assay clotting time compared to a control plasma. The method and test kit is used to diagnose thrombic diseases.

REFERENCES:
patent: 3486981 (1969-12-01), Speck
patent: 4705756 (1987-11-01), Spillert et al.
patent: 4908314 (1990-03-01), Orthner
Martinoli et al, Chemical Abstracts, vol. 105, Abstract No. 105:93300x, 1986.
Kirk-Othmer vol. 4, pp. 1 to 24 (1978).

Affiliated with

Also associated with

Rating

Method and assay using inactivation of factors Va and VIIIa by a does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and assay using inactivation of factors Va and VIIIa by a, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and assay using inactivation of factors Va and VIIIa by a will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1696401