Method and assay for regulation of T cell proliferation

Details Method and assay for regulation of T cell proliferation Method and assay for regulation of T cell proliferation

1996-12-31

2000-03-21

Chan, Christina Y.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435 71, 435 724, 435325, C12Q 102

Patent

active

060401524

ABSTRACT:
The present invention discloses a method to regulate T cell proliferation by regulating protein kinase C theta (PKC.theta.) in a T cell. Also disclosed are assays for evaluating the ability of a T cell to proliferate in response to an antigen-specific stimulus, a method to regulate T cell proliferation in a mammal in vivo, a method to identify compounds which regulate T cell proliferation, and compounds identified thereby.

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