Method and arrangement for analyzing samples

Details Method and arrangement for analyzing samples Method and arrangement for analyzing samples

2003-05-14

2008-09-02

Toatley, Jr., Gregory J (Department: 2877)

Optics: measuring and testing

By dispersed light spectroscopy

With sample excitation

C356S317000, C356S417000, C250S458100, C250S461200

Reexamination Certificate

active

07420674

ABSTRACT:
A method and/or arrangement for the analysis of fluorescing samples in an image-generating microscope system, preferably a laser scanning microscope, wherein the sample is scanned point-by-point or line-by-line in at least one surface section and a dispersive splitting of the radiation coming from the sample is carried out during the scanning, wherein the split radiation is detected by at least one line of detector elements in a wavelength-dependent manner, a selection of two-dimensional or three-dimensional sample parts which correspond to pre-stored two-dimensional or three-dimensional geometric objects or the like is carried out based on the recorded and stored intensity distribution of at least one of these detection elements and/or at least one other detection element for the radiation reflected from the sample by image processing, and an analysis of the spectral signature and/or spatial spectral sequence is carried out for at least a portion of these sample regions with respect to the fluorescence markers arranged thereon.

REFERENCES:
patent: 5510894 (1996-04-01), Batchelder et al.
patent: 5784162 (1998-07-01), Cabib et al.
patent: 5936731 (1999-08-01), Cabib et al.
patent: 7064813 (2006-06-01), Takahashi et al.
patent: 2002/0044272 (2002-04-01), Basiji et al.
patent: 2002/0180965 (2002-12-01), Engelhardt et al.
patent: 197 02 753 (1998-07-01), None
patent: 197 13 362 (1998-10-01), None
patent: 198 35 072 (2000-02-01), None
patent: 198 42 288 (2000-02-01), None
patent: 198 59 314 (2000-06-01), None
patent: 100 38 526 (2002-02-01), None
patent: 100 38 528 (2002-02-01), None
patent: 100 33 180 (2002-05-01), None
patent: WO 02/01222 (2002-01-01), None
Pawley, “Handbook of Biological Confocal Microscopy”; Plenum Press 1995.
Corle, Kino, “Confocal Scanning, Optical Microscopy and Related Imaging Systems”; Academic Press 1996.
“Flow Cytometry and Sorting”, second edition, M. R. Melamed, T. Lindmo, M. L. Mendelsohn, eds., Wiley & Sons, Inc., New York, 1990, pp. 81-107.
PCA, I.T. Joliffe,Principal Component Analysis, Springer-Verlag, New York, 1986.
Chemical Analysis, vol. 137, Chapter 4, pp. 87-124“Spectral Bio-Imaging” Y. Garini, et al.
XP002257573: Zeiss Brochure (online) Nov. 2000(200-11), “Anonymous: Cell Observer: Leben mit neuen Augen sehen”.
XP02257574: Phys. Med. Biol (online) 1996, pp. 523-537 “Automated cell cycle analysis with fluorescence microscopy and image analysis” W. Buecker, et al.
XP002257575: Zeiss News (online) May 2002, pag 1-2, Anonymous: Particle Analyser: Schnelle Durchfuehrung Dokumentations- und Messaufgaben.
XP002257576: Zeiss Brochure (online), Anonymous: Particle Analyser—Die Funktionen.

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