Method and appartatus for improved time-resolved fluorescence sp

Details Method and appartatus for improved time-resolved fluorescence sp Method and appartatus for improved time-resolved fluorescence sp

1987-03-27

1989-08-08

Lall, Parshotam S.

Boots, shoes, and leggings

2504581, 356318, 364554, G01J 158, G06F 1520

Patent

active

048559300

ABSTRACT:
A method and apparatus for time-resolved fluorescence spectroscopy is described in which laser light from a single pulse is used to excite fluorescent photons in a sample, which fluorescence is detected by a PMT optimized for linearity and response time to produce photoelectrons which generate a current at the PMT anode. This current is discharged through an R/C network to produce a voltage amplitude waveform which is converted to an optical image, intensified, stored and digitized. The digitized version of the optical image is processed in a data processor to calculate the true fluorescence impulse response.

REFERENCES:
patent: 4035080 (1977-07-01), Yamaguchi
patent: 4058732 (1977-11-01), Wieder
patent: 4198567 (1980-04-01), Eneroth et al.
patent: 4231750 (1980-11-01), Dowben et al.
patent: 4330207 (1982-05-01), Nogami et al.
patent: 4368047 (1983-01-01), Andrade et al.
patent: 4385126 (1983-05-01), Chen et al.
patent: 4511986 (1985-04-01), Bellar et al.
patent: 4582809 (1986-04-01), Block et al.
patent: 4641032 (1987-02-01), Mauchien et al.
patent: 4652755 (1987-03-01), Solomon et al.
G. T. Longerbeam et al.: "High Speed Single Transient Oscilloscopes, the State of the Art, and Current Potential for Mating to On-Line Computers", pp. 13/4:1-10 w/ 1969 Wescon Technical Papers, Part 4, Instruments and Systems, Western Electronic Show and Convention, 19-22, Aug. 1969 (US).
"Subnanosecond Fluorescence Waveforms Measurements with a Dual Time-Scale Microprocessor-Controlled Averager", Docchio et al., Rev. Sci. Instrum., 52(11), Nov. 1981, pp. 1671-1675.
R. I. Sha'afi et al., "Fast Methods in Physical Biochemistry and Cell Biology", 1983, published by Elsevier, pp. 221-279.
"Applications of Lasers in Analytical Molecular Fluorescence Spectroscopy", Modern Fluorescence Spectroscopy, vol. 4, 1981, J. H. Richardson, p. 15.
"A High Sensitivity Television Camera System for Pico-Second Spectroscopy", pp. 947-948, Japanese Journal of Applied Physics, vol. 15, No. 5, 1976, H. Saito et al.
"Time-Resolved Fluorescence Spectroscopy", Salvador M. Fernandez, Fast Methods in Physical Biochemistry and Cell Biology, Elsevier Science Publishers, 1983, pp. 221-280.

Affiliated with

Also associated with

Rating

Method and appartatus for improved time-resolved fluorescence sp does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and appartatus for improved time-resolved fluorescence sp, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and appartatus for improved time-resolved fluorescence sp will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-910904