Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Reexamination Certificate
2005-01-31
2009-08-25
Shukla, Ram R. (Department: 1634)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
C435S091100, C435S283100, C204S450000
Reexamination Certificate
active
07579149
ABSTRACT:
A method and apparatus for separating molecules comprises placing different kinds of molecular species onto a probe; and introducing an electric field between the probe and a surface in proximity with the probe so that the different kinds of molecular species may be separated, wherein the different kinds of molecular species have differing mobilities, and wherein the different kinds of molecular species may be separated according to their differing mobilities, such that molecular species that have different mobilities migrate along the probe at different speeds towards the surface. The molecular species may comprise molecules. Alternatively, the molecular species may comprise molecular assemblies, wherein the molecular assemblies may comprise at least one of cells, bacteria, and viruses.
REFERENCES:
patent: 4206160 (1980-06-01), Suddendorf et al.
patent: 4539089 (1985-09-01), Binnig et al.
patent: 5144148 (1992-09-01), Eigler
patent: 5689494 (1997-11-01), Ichikawa et al.
patent: 5869829 (1999-02-01), Dresch
patent: 5980713 (1999-11-01), Davidson et al.
patent: 6051189 (2000-04-01), Wick et al.
patent: 6350609 (2002-02-01), Morozov et al.
patent: 6716994 (2004-04-01), Menchen et al.
patent: 2002/0122873 (2002-09-01), Mirkin et al.
patent: 2002/0125192 (2002-09-01), Lopez et al.
patent: 2003/0157254 (2003-08-01), Mirkin et al.
patent: 2003/0190647 (2003-10-01), Odera
patent: 2004/0037959 (2004-02-01), Mirkin et al.
patent: 2004/0214177 (2004-10-01), Bension
Gardiner et al, Somatic Cell Mol. Genet., vol. 12, pp. 185-195 (1986).
Descruisseaux et al. “Electrophoresis of Composite Molecular Objects. 2. Competition Between Sieving and Frictional Effects in Polymer Solutions”, Macromolecules 2001. vol. 34, pp. 5280-5286.
Mayer et al. “Theory of DNA Sequencing Using Free-Solution Electrophoresis of Protein-DNA Complexes”, Analytical Chemistry, vol. 66, No. 10, May 15, 1994, pp. 1777-1780.
Frommer Jane E.
Unal Kerem
Wickramasinghe Hemantha K.
Crow Robert T.
Gibb I.P. Law Firm LLC
International Business Machines - Corporation
Shukla Ram R.
LandOfFree
Method and apparatus to separate molecules according to... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and apparatus to separate molecules according to..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and apparatus to separate molecules according to... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4067536