Method and apparatus of increasing dynamic range and sensitivity

Details Method and apparatus of increasing dynamic range and sensitivity Method and apparatus of increasing dynamic range and sensitivity

1995-03-03

1996-11-05

Anderson, Bruce C.

Radiant energy

Ionic separation or analysis

Methods

250292, H01J 4900, B01D 5944

Patent

active

055720226

ABSTRACT:
This invention is directed to a method and apparatus of increasing the dynamic range and sensitivity of an ion trap mass spectrometer with the use of external ionization. An increased number of sample ions are introduced into the mass spectrometer for mass analysis with the aid of an automatic ion supply control, or feedback, feature. The feedback portion of the invention controls the gating time, and hence the number of sample ions gated into the mass spectrometer, based on previous measurements of the ion content in the mass spectrometer to gate an amount relative to where space charge and saturation begins. A mass filter may also be used between the ion source and the mass spectrometer to improve the signal-to-noise ratio and increase the net processing time. This mass analyzing system may be used with various methods of mass analysis including mass selective instability, resonance ejection, MS/MS, and MS/MS with a supplemental AC field.

REFERENCES:
patent: Re34000 (1992-07-01), Syka et al.
patent: 2939952 (1960-06-01), Paul et al.
patent: 3527939 (1970-09-01), Dawson et al.
patent: 3742212 (1973-06-01), McIver, Jr.
patent: 4540884 (1985-09-01), Stafford et al.
patent: 4736101 (1988-04-01), Syka et al.
patent: 5107109 (1992-04-01), Stafford
patent: 5206507 (1993-04-01), Kelley
patent: 5285063 (1994-02-01), Schwartz et al.
patent: 5420425 (1995-05-01), Bier et al.

Affiliated with

Also associated with

Rating

Method and apparatus of increasing dynamic range and sensitivity does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and apparatus of increasing dynamic range and sensitivity, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and apparatus of increasing dynamic range and sensitivity will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2016452