Method and apparatus of a defined serumfree medical solution

Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Ophthalmic preparation

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435 1, 4352402, 4352403, A61K 3174, A01N 102, C12N 500

Patent

active

054076692

ABSTRACT:
A defined serumfree medical solution for applications in Ophthalmology, that contains one or more cell nutrient supplements which maintains and enhances the preservation of eye tissues, including human corneal tissues at low temperatures (2.degree. C. to 15.degree. C.). This solution is composed of a defined aqueous nutrient and electrolyte solution, supplemented with a glycosaminoglycan(s), a deturgescent agent(s), an energy source(s), a buffer system(s), an antioxidant(s), membrane stabilizing components, antibiotic(s), ATP precursors and nutrient cell supplements.

REFERENCES:
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patent: 4725586 (1988-02-01), Lindstrom et al.
patent: 4886786 (1989-12-01), Lindstrom et al.
patent: 5104787 (1992-04-01), Lindstrom et al.
Couch et al., "Mitotic Activity of Corneal Endothelial Cells in Organ Culture with Recombinant Human Epidermal Growth Factor", Ophthalmology, Jan., 1987, vol. 94, No. 1, pp. 1-4.

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