Method and apparatus for wash, resuspension, recollection and lo

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

436 47, 436807, 436809, 209214, 210222, 210695, 4352871, 4352872, 4352873, 422 65, 422 681, 422101, 422102, G01N 33553, G01N 3502, B03C 100, B01D 3506, C12M 100

Patent

active

061435783

ABSTRACT:
Method and apparatus for enabling resuspension wash and magnetic localization of sample components bound to particles with magnetic properties in reaction vessels during separation and wash for enhanced chemiluminescent signal generation in biomedical assays. The assays involve moving reaction vessels past magnets that partially localize the particles prior to passing a reduced strength magnet where washing occurs, with or without resuspension, after separating out the unbound particles and liquid. The band of particles is subsequently resuspended in acid for chemiluminescent purposes. A variety of magnet configurations are employed to realize the reduced strength magnet. Reduced strength magnets adjacent the full width magnets prevent the band of magnetic particles from becoming split. The localized particles enable more efficient resuspension by reagent.

REFERENCES:
patent: 4265855 (1981-05-01), Mandle et al.
patent: 4628037 (1986-12-01), Chagnon et al.
patent: 4661408 (1987-04-01), Lau et al.
patent: 4698302 (1987-10-01), Whitehead et al.
patent: 4745077 (1988-05-01), Holian et al.
patent: 4785407 (1988-11-01), Sakagami
patent: 5104808 (1992-04-01), Laska et al.
patent: 5108933 (1992-04-01), Liberti et al.
patent: 5128103 (1992-07-01), Wang et al.
patent: 5147529 (1992-09-01), Lee et al.
patent: 5183638 (1993-02-01), Wakatake
patent: 5186827 (1993-02-01), Liberti et al.
patent: 5200084 (1993-04-01), Liberti et al.
patent: 5232665 (1993-08-01), Burkovich et al.
patent: 5256532 (1993-10-01), Melnicoff et al.
patent: 5278080 (1994-01-01), Midgley et al.
patent: 5283079 (1994-02-01), Wang et al.
patent: 5374531 (1994-12-01), Jensen
patent: 5395688 (1995-03-01), Wang et al.
patent: 5466574 (1995-11-01), Liberti et al.
patent: 5491068 (1996-02-01), Benjamin et al.
patent: 5741708 (1998-04-01), Carey et al.
Advanced Magnetics Inc. (Jul. 1984) "Instructions and Precautions for Handling Biomag".

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method and apparatus for wash, resuspension, recollection and lo does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and apparatus for wash, resuspension, recollection and lo, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and apparatus for wash, resuspension, recollection and lo will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1639665

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.