Method and apparatus for volumetric interstitial conductive hype

Surgery – Truss – Pad

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

128401, 128784, 606 13, 606 27, A61F 712

Patent

active

051974665

ABSTRACT:
A system and method for producing volumetric conductive hyperthermia for the treatment of a cancerous tumor in a patient. The location and volume of the tumor are determined with the aid of a CT scanning system, and an array of probes each containing a heat-emitting element is formed by interstitial implantation in the tumor in a predetermined pattern for volumetric heating using a template for guiding the probes into parallel alignment in the tumor. The template is affixed with respect to the patient's body and with respect to the imaging plane of the CT scanning system. After implantation, the probes are connected to a manifold which is in turn connected to an external control system capable of independently controlling the probes while monitoring various analog and digital values representative of system performance.

REFERENCES:
patent: 2777445 (1957-01-01), Hart
patent: 3088027 (1963-04-01), Graham
patent: 3170465 (1965-02-01), Henney et al.
patent: 3231834 (1966-01-01), Watanabe
patent: 3369549 (1968-02-01), Armao
patent: 3404678 (1968-10-01), Von Ardenne
patent: 3453546 (1969-07-01), Fryer
patent: 3508552 (1970-04-01), Hainault
patent: 3698394 (1972-10-01), Piper et al.
patent: 3714428 (1973-01-01), Gasaway
patent: 3717140 (1973-02-01), Greenwood
patent: 3817249 (1974-06-01), Nicholson
patent: 3901224 (1975-08-01), Bucalo
patent: 3938526 (1976-02-01), Anderson et al.
patent: 3942535 (1976-03-01), Schulman
patent: 3949388 (1976-04-01), Fuller
patent: 3972320 (1976-08-01), Kalman
patent: 3991770 (1976-11-01), LeVeen
patent: 4016886 (1977-04-01), Doss et al.
patent: 4046139 (1977-09-01), Horn
patent: 4119102 (1978-10-01), LeVeen
patent: 4121592 (1978-10-01), Whalley
patent: 4127110 (1978-11-01), Bullara
patent: 4142529 (1979-03-01), Latenser et al.
patent: 4146029 (1979-03-01), Ellinwood
patent: 4166451 (1979-09-01), Salera
patent: 4181132 (1980-01-01), Parks
patent: 4182313 (1980-01-01), Aslan
patent: 4186729 (1980-02-01), Harrison
patent: 4204549 (1980-05-01), Paglione
patent: 4210152 (1980-07-01), Berry
patent: 4223678 (1980-09-01), Langer et al.
patent: 4227535 (1980-10-01), Connor
patent: 4232679 (1980-11-01), Schulman
patent: 4237900 (1980-12-01), Schulman et al.
patent: 4275738 (1981-06-01), McDonald et al.
patent: 4298006 (1981-11-01), Parks
patent: 4312364 (1982-01-01), Convert et al.
patent: 4331161 (1982-05-01), Patel
patent: 4333469 (1982-06-01), Jeffcoat et al.
patent: 4341220 (1982-07-01), Perry
patent: 4346725 (1982-08-01), Gammell
patent: 4352960 (1982-10-01), Dormer et al.
patent: 4360028 (1982-11-01), Barbier et al.
patent: 4427005 (1984-01-01), Tener
patent: 4448198 (1984-05-01), Turner
patent: 4465069 (1984-08-01), Barbier et al.
patent: 4475550 (1984-10-01), Bremer et al.
patent: 4483341 (1984-11-01), Witteles
patent: 4580561 (1986-04-01), Williamson
patent: 4586490 (1986-05-01), Katz
patent: 4612940 (1986-09-01), Kasevich et al.
patent: 4618978 (1986-10-01), Cosman
patent: 4638436 (1987-01-01), Badger et al.
patent: 4669475 (1987-06-01), Turner
patent: 4679561 (1987-07-01), Doss
patent: 4691333 (1987-09-01), Gabriele et al.
patent: 4695709 (1987-09-01), Sachs et al.
patent: 4712559 (1987-12-01), Turner
patent: 4719919 (1988-01-01), Marchosky et al.
patent: 4739771 (1988-04-01), Manwaring
patent: 4744370 (1988-05-01), Harris
patent: 4776086 (1988-10-01), Kasevich et al.
patent: 4791934 (1988-12-01), Brunnett
patent: 4800899 (1989-01-01), Elliott
patent: 4947842 (1990-08-01), Marchoski et al.
patent: 4961422 (1990-10-01), Marchosky et al.
patent: 4989601 (1991-02-01), Marchosky et al.
Hornback, Ned B., "Hyperthermia and Cancer," (CRC Press, Boca Raton, Fla., 1984), vol. II, Chapter I.
Storm, F. Kristian, "Hyperthermia in Cancer Therapy," (G. K. Hall Medical Publishers, Boston, 1983), Table of Contents.
Nussbaum, Gilbert H., "Physical Aspects of Hyperthermia," (American Institute of Physics, New York, 1982), Table of Contents.
Parsonnet et al., "An Experimental Method for Thermal Control of Heart Rate: Work In Progress," PACE, Sep.-Oct., 1980.
Murawski et al., "An Externally Programmable, Implantable, Integrated Cerebellar Stimulator," IEEE in Medicine & Biology Society, 1982.
Taylor, "Brain Cancer Therapy Using an Implanted Microwave Radiator," Microwave Journal, 1981.
Sutton, Carl H., "Tumor Hyperthermia in the Treatment of Malignant Gliomas of the Brain," Transactions of the American Neurological Association, 96:195-199, 1971.
Anghileri, Leopold et al. [Eds.], Hyperthermia in Cancer Treatment, CRC Press, Inc., Boca Raton, Florida, 1986, vol. II, pp. 126, 136-138; vol. III, pp. 26, 44.
Pacela et al., "New Copolymer Will Administer Brain Cancer Drug," Biomedical Technology, vol. 14, No. 24, Nov. 15, 1987, p. 244.
Mulcahy, "Hyperthermia and Chemotherapy," Syllabus: A Categorical Course in Radiator Therapy: Hyperthermia, Radiological Society of North America, Nov. 29-Dec. 4, 1987, pp. 27-35.
Tamargo et al., "Growth Inhibition of the 9L Gliosarcoma by the Local Sustained Release of BCNU: A Comparison of Systemic versus Regional Chemotherapy," Scientific Program: The Meeting of the American Association of Neurological Surgeons, Apr. 24-28, 1988, Toronto, Ontario p. 212.
Brem et al., "A Biodegradable Polymer for Intracranial Drug Delivery: A Radiological Study in Primates," Scientific Program: The Annual Meeting of the American Association of Neurological Surgeons, Apr. 24-28, 1988, Toronto, Ontario, pp. 381-382.
Brem et al., "Biocompatibility of a BCNU-Loaded Biodegradable Polymer: A Toxicity Study in Primates," Scientific Program: The Annual meeting of the American Association of Neurological Surgeons, Apr. 24-28, 1988, Toronto, Ontario, pp. 381-382.
Tamargo et al., "Brain Biocompatibility of a Biodegradable Polymer Capable of Sustained Release of Macromolecules," Scientific Program: The Annual Meeting of the American Association of Neurological Surgeons, Apr. 24-28, 1988, Toronto, Ontario, pp. 399-400.
Yang et al., "Sustained Systemic Delivery of BCNU from an Intraperitoneal Polymer Implant," Scientific Program: The Annual Meeting of the American Association of Neurological Surgeons, Apr. 24-28, Toronto, Ontario, p. 414.
Leong et al., "Bioerodible polyanhydrides as drug-carrier matrices. II. Biocompatibility and chemical reactivity, Journal of Biomedical Materials Research, vol. 20, 1986, pp. 51-64.
Leong et al., "Bioerodible Polyanhydrides for Cancer Chemotherapy," Proceed. Intern. Symp. Control. Bioact. Mater., 12, 1985, pp. 106-107.
Rosen et al., "Bioerodible Polyanhydrides for Controlled Drug Delivery," Biomaterials, 1983, vol. 4, Apr., pp. 131-133.
Leong et al., "Bioerodible polyanhydrides as drug-carrier matrices. I: Characterization, degradation, and release characteristics," Journal of Biomedical Materials Research, vol. 19, 1985, pp. 941-955.
Beck et al., "An Overview of the FDA Approved Controlled-Release Polymeric Materials," Proceed Intern. Symp. Control. Rel. Bioact. Mater., 12, 1985, p. 214.
Langer, Robert S., "New Drug Delivery Systems: What the Clinician Can Expect," Drug Therapy, Apr., 1983, pp. 217-231.
Langer, et al., "Biocompatibility of Polymeric Delivery Systems for Macromolecules," Journal of Biomedical Materials Research, vol. 15, 1981, pp. 267-277.
Kenealy, Dr. J., "Safety and Efficacy of BCNU Delivered From a Biodegradable, Surgically Implanted Polymer For the Treatment of Grade III or IV Astrocytoma, Protocol NPC8701, Nova Pharmaceutical Corp., pp. 1-15.
"Treatment of Grade III and IV Anaplastic Glioma By Means of Controlled Release of Carmustine (BCNU) from Biodel.TM., a Biodegradable Polymer," Investigator's Brochure, Nova Pharmaceutical Corporation, Jul. 20, 1988, pp. 1-32.
Brem et al., "Biocompatibility of a Biodegradable, Controlled-Release Polymer in the Rabbit Brain," The John Hopkins University School of Medicine, Baltimore, Md., 1988.
Grossman et al., "The Intracerebral Delivery of BCNU with Surgically Implanted Biodegradable Polymers: A Quantitative Autoradiographic Study, Proceedings of ASCO, vol. 7, Mar., 1988, p. 84.
Weiss, Rick, "Delivering the Goods: Designing a New Drug is One Thing; Getting it to the Disease is

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method and apparatus for volumetric interstitial conductive hype does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method and apparatus for volumetric interstitial conductive hype, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and apparatus for volumetric interstitial conductive hype will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1274703

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.