Surgery – Diagnostic testing – Cardiovascular
Patent
1997-11-04
1999-07-13
Kamm, William E.
Surgery
Diagnostic testing
Cardiovascular
A61N 50452
Patent
active
059219408
ABSTRACT:
The non-invasive, dynamic tracking and diagnosing of cardiac vulnerability to ventricular fibrillation involves analysis of both cardiac electrical stability and the influence of autonomic activity. The magnitude of alternation in an electrocardiogram is indicative of cardiac electrical stability. Alternans are made manifest by applying a physiologic stress such as exercise or behavioral stress to a subject.
REFERENCES:
patent: 3215136 (1965-11-01), Holter et al.
patent: 3554187 (1971-01-01), Glassner et al.
patent: 3658055 (1972-04-01), Abe et al.
patent: 3759248 (1973-09-01), Valiquette
patent: 3828768 (1974-08-01), Douglas
patent: 3902479 (1975-09-01), Chaumet
patent: 4023564 (1977-05-01), Valiquette et al.
patent: 4170992 (1979-10-01), Dillman
patent: 4492235 (1985-01-01), Sitrick
patent: 4583553 (1986-04-01), Shah et al.
patent: 4622980 (1986-11-01), Kunig
patent: 4665485 (1987-05-01), Lundy et al.
patent: 4679144 (1987-07-01), Cox et al.
patent: 4680708 (1987-07-01), Ambos et al.
patent: 4732157 (1988-03-01), Kaplan et al.
patent: 4796638 (1989-01-01), Sasaki
patent: 4802491 (1989-02-01), Cohen et al.
patent: 4924875 (1990-05-01), Chamoun
patent: 4972834 (1990-11-01), Begemann et al.
patent: 4974162 (1990-11-01), Siegel et al.
patent: 5010888 (1991-04-01), Jadvar et al.
patent: 5020540 (1991-06-01), Chamoun
patent: 5042497 (1991-08-01), Shapland
patent: 5046504 (1991-09-01), Albert et al.
patent: 5092341 (1992-03-01), Kelen
patent: 5109862 (1992-05-01), Kelen et al.
patent: 5148812 (1992-09-01), Verrier et al.
patent: 5188116 (1993-02-01), Pommrehn et al.
patent: 5234404 (1993-08-01), Tuttle et al.
patent: 5265617 (1993-11-01), Verrier et al.
patent: 5277190 (1994-01-01), Moulton
patent: 5299119 (1994-03-01), Kraf et al.
patent: 5323783 (1994-06-01), Henkin et al.
patent: 5570696 (1996-11-01), Arnold et al.
Adam et al., "Estimation of Ventricular Vulnerability to Fibrillation ThroughT-Wave Time Series Analysis," 1982 IEEE, Reprinted from Computers in Cardiology, Sep., 1981, pp. 307-310.
Adam, et al., "Fluctuations in T-Wave Morphology and Susceptibility to Ventricular Fibrillation," J. Electrocardiology, 17(3), 1984, pp. 209-218.
Adam et al., "Ventricular Fibrillation and Fluctuations in the Magnitude of the Repolarization Vector," 1982 IEEE. Computers in Cardiology, pp. 241-244.
Akselrod et al., "Power Spectrum Analysis of Heart Rate Fluctuation: A Quantitive Probe of Beat-to-Beat Cardiovascular Control," Science , vol. 213, Jul. 10, 1981, pp. 220-222.
Appel et al., "Beat to Beat Variability in Cardiovascular Variables: Noise or Music?," JACC, vol. 14, No. 5, Nov. 1, 1989, pp. 1139-1148.
Appel et al., "Closed-Loop Identification of Cardiovascular Regulatory Mechanisms," IEEE, 1990, pp. 3-8.
Barbieri et al., "Continuous Quantification of Baroreflex and Respiratory Control of Heart Rate by Use of Bivariate Autoregressive Techniques," Anals of Noninvasive Electrocardiology, Jul., 1996, vol. 1, No. 3, pp. 264-277.
Belic et al., "ECG Manifestations of Myocardial Ischemia," Arch Intern Med, Cardiologic Diagnosis, vol. 140, Sep., 1980, pp. 1162-1165.
Bigger, Jr., et al., "Comparison of Time and Frequency Domain-Based Measures of Cardiac Parasympathetic Activity in Holter Recordings After Myocardial Infarction," The American Journal of Cardiology, vol. 64, 1989, pp. 536-538.
Bigger, Jr., et al., "Correlations Among Time and Frequency Domain Measures of Heart Period Variability Two Weeks After Acute Myocardial Infarction," The American Journal of Cardiology, vol. 69, Apr. 1, 1992, pp. 891-898.
Bigger, Jr., et al., "Stability Over Time of Heart Period Variability in Patients With Previous Myocardial Infarction and Ventricular Arrhythmias," The American Journal of Cardiology, vol. 69, Mar. 15, 1992, pp. 718-723.
Day et al., "QT Dispersion: An Indication of Arrhythmia Risk In Patients With Long QT Intervals," British Heart Journal ISSN 007-0769, Jun. 1990,
Doue et al., Computer-Aided ECG Analysis, 1266 Hewlett-Packard Journal, 36 Sep. 1985, No. 9, Amstelveen, Netherlands, pp. 29-34.
Dower et al., "A New System for ECG Analysis Oriented Toward Polarcardiology," Computers in Cardiology Conference, Rotterdam, Netherlands, Sep. 29-Oct. 1, 1977, pp. 497-501.
Farrell et al., "Risk Stratification for Arrhythmic Events in Postinfarction Patients Based on Heart Rate Variability, Ambulatory Electrocardiographic Variables and the Signal-Averaged Electrocardiogram," JACC, vol. 18, No. 3, Sep., 1991, pp. 687-697.
Freeman et al., "Spectral Analysis of Heart Rate in Diabetic Autonomic Neuropathy," Arch Neurol, vol. 48, Feb., 1991, pp. 185-190.
Goovaerts et al., "A Digital QRS Detector Based on the Principle of Contour Limiting," IEEE Transactions on Biomedical Engineering, vol. BME-23, No. 2, Mar., 1976, pp. 154-160.
Guyton, M.D., Textbook of Medical Physiology, Third Edition, Respiration, Regulation of Respiration, 1966, pp. 600-603.
Hayano et al., "Accuracy of Assessment of Cardiac Vagal Tone by Heart Rate Variability in Normal Subjects," The American Journal of Cardiology, vol. 67, Jan. 15, 1991, pp. 199-204.
Hii et al., "Precordial QT Interval Dispersion as a Marker of Torsade de Pointes: Disparate Effects of Class Ia Antiarrhythmic Drugs and Only!.
Joyal et al., "ST-Segment Alternans During Percutaneous Transluminal Coronary Angioplasty," Brief Reports, 1984, pp. 915-916.
Kiauta et al., "Complex Demodulation of Heart Rate Changes During Othostatic Testing," IEEE Proceedings: Computers in Cardiology, 1990, pp. 159-162.
Kleiger et al., "Stability Over Time of Variables Measuring Heart Rate Variability in Normal Subjects," The American Journal of Cardiology, vol. 68, Sep. 1, 1991, pp. 626-630.
La Rovere et al., "Baroreflex Sensitivity, Clinical Correlates, and Cardiovascular Mortality Among Patients With a First Myocardial Infarction," Circulation, vol. 78, No. 4, Oct., 1988, pp. 816-824.
Lombardi et al., "Relationship Between Sympathetic Neural Activity, Coronary Dynamics, and Vulnerability to Ventricular Fibrillation During Myocardial Ischemia and Reperfusion," American Heart Journal, St. Louis, vol. 105, No. 6, Jun., 1983, pp. 958-965.
Malpas et al., "Heart-Rate Variability and Cardiac Autonomic Function in Diabetes," Diabetes, vol. 39, Oct., 1990, pp. 1177-1181.
Meloni et al., "An Analysis of the Variability in the Heart Rate in Relation to the Presence of Transient Ischemia and to its Physiopathological Mechanism," Cardiologia, vol. 37(1), 1991, pp. 35-41.
Moss, "Measurement of the QT Interval and the Risk Associated with QT.sub.c Interval and the Risk Associated with QT.sub.c Interval Prolongation: A Review," The American Journal of Cardiology, vol. 72, Aug. 26, 1993, pp. 23B-25B.
Myers et al., "Power Spectral Analysis of Heart Rate Variability in Sudden Cardiac Death: Comparison to Other Methods," IEEE Transactions on Biomedical Engineering, vol. BME-33, No. 12, Dec. 1986, pp. 1149-1156.
Nearing et al., "Dynamic Tracking of Cardiac Vulnerability by Complex Demodulation of the T-Wave," Science, vol. 252, Apr. 19, 1991, pp. 437-440.
Nearing et al., "Simultaneous Assessment of Autonomic Regulation and Cardiac Vulnerability During Coronary Occlusion and Reperfusion by Complex Demodulation of Heart Rate Variability and T-Wave Alternans," Circulation,
Orr et al., "A 90-Min Cardiac Biorhythm: Methodology and Data Analysis Using Modified Periodograms and Complex Demodulation," IEEE Transactions on Biomedical Engineering, vol. BME-21, No. 2, Mar., 1974, pp. 130-143.
Pagani et al., "Power Spectral Analysis of Heart Rate and Arterial Pressure Variabilities asa Marker of Sympatho-Vagal Interaction in Man and Conscious Dog," Circulation Research, vol. 59, No. 2, Aug., 1986, pp. 178-193.
Pozzi et al., "A Noninvasive Assessment of the Gain in Baroceptor Control of the Heart Rate in Man," Cardiologia, 37(10), Oct., 1992, pp. 729-737.
Raeder et al., "Alternating Morphology of the QRST Complex Preceding Sudden Death," The New England Journal of Medicine, vol. 326, No. 4, Jan. 23, 1992, pp. 271-272.
Ritzenberg et al., "Period Multupling-Evidence for Nonlinear Behavior of the Canine Heart," Nature, vol. 30
Nearing Bruce D.
Verrier Richard L.
Georgetown University
Kamm William E.
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