Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Reexamination Certificate
2007-03-20
2007-03-20
Gitomer, Ralph (Department: 1657)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
C530S350000, C435S288700
Reexamination Certificate
active
10313010
ABSTRACT:
An apparatus and method for detecting infrared radiation is provided which comprises a temperature-sensing helical coiled-coil protein such as TlpA, CC1, collagen or myosin, incorporated into an electrically conductive film or gel deposited onto an electrically conductive medium such as an electrode, means for recording changes in conductivity or resistance of the conductive film or gel caused by the presence of infrared radiation and the effect of the infrared radiation on the thermal-sensing protein, and means to analyze the changes in conductivity or resistance in the conductive film caused by the infrared radiation so as to determine if infrared radiation is present. By virtue of the present invention, a “biomimetic” infrared sensor is provided which can integrate a recombinantly produced thermally sensitive protein in a conductive polymer matrix, such as a film or gel, so as to provide for the first time a low-cost, lightweight, conformable, and even possibly disposable, infrared detecting device having high sensitivity and excellent dynamic range.
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Brott Lawrence L.
Carter Daniel C.
Naik Rajesh R.
Stone Morley O.
Gitomer Ralph
New Century Pharmaceuticals Inc.
Schulman B. Aaron
Stites & Harbison PLLC
The United States of America as represented by the Secretary of
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