Method and apparatus for ultra-high sensitivity optical...

Details Method and apparatus for ultra-high sensitivity optical... Method and apparatus for ultra-high sensitivity optical...

2006-05-30

2006-05-30

Lauchman, Layla G. (Department: 2877)

Optics: measuring and testing

For light transmission or absorption

Of fluent material

C356S440000, C422S082090

Reexamination Certificate

active

07054009

ABSTRACT:
Combining the approaches of cavity ring down spectroscopy with surface plasmon resonance spectroscopy allows creation of an ultra-high sensitivity apparatus to detect extremely low concentrations of chemicals and biomolecules.

REFERENCES:
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patent: 5835231 (1998-11-01), Pipino
patent: 6515749 (2003-02-01), Pipino
patent: 2002/0122179 (2002-09-01), Pipino
Pipano, A.C.R. et al., “Evanescent Wave Cavity Ring-Down Spectroscopy with a Total-Internal-Reflection Minicavity”, American Institute of Physics, New York, US vol. 68, No. 8, Aug. 1, 1997, pp. 2978-2989.
Haes, Amanda J. et al., “A Nanoscale Optical Biosensor: Sensitivity and Selectivity of an Approach Based on the Localized Surface Plasmon Resonance Spectroscopy of Triangular Silver Nanoparticlaes”, J.Am.Chem.Soc, 2002, 124, pp. 10596-10604.
Bjorklund, Gary C., “Frequency-Modulation Spectroscopy: A New Method for Measuring Weak Absorptions and Dispersions”, Optics Letters, vol. 5, No. 1, Jan. 1980, pp. 15-17.
Engelin, Richard et al., “Phase Shift Cavity Riing Down Absorption Spectroscopy”, Chemical Physics Letters, 262, Nov. 8, 1996, pp. 105-109.
Pipino, Andrew C.R., “Evanescent Wave Cavity Ring-Down Spectroscopy with a Total-Internal-Reflection Minicavity”, Rev.Sci.Instrum. vol. 68, No. 8, Aug. 1997, pp. 2978-2989.
Armani, D.K., “Ultra-High-Q Toroid Microavity on a Chip”, Letters to Nature, vol. 421, Feb. 2003, pp. 925-928.

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