Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1997-08-01
1999-10-05
Azpuru, Carlos A.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
A61F 202
Patent
active
059620048
ABSTRACT:
A method and implants provide for relieving pressure from a region of the brainstem within the cranium of a subject with a neuroendocrine servomechanism. The pressure results from the compression of the region by a blood vessel. The method includes gaining access to the region using a first surgical technique; exposing the region according to a second surgical technique; lifting the blood vessel from the region according to a third surgical technique, thereby providing the pressure relief; and inserting a neurovascular bridge implant between the blood vessel and the region to maintain the pressure relief. The neuroendocrine servomechanism is responsive to the pressure relief on the region, causing amelioration of a disease. One neuroendocrine servomechanism can include the pancreas of the subject, and the pressure relief ameliorates non-insulin-dependent diabetes mellitus. The neurovascular bridge implant can be a preconfigured shredded plastic implant, made of polytetrafluoroethylene, or a preconfigured thermoplastic implant, made of a polyurethane-based material having a glass-transition temperature of between 20.degree. C. to 60.degree. C. and a transition band of about 8.degree. C.
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From the Divisions of Physiological Acoustics, Audiology and Speech Pathology, "Neural Generators
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