Surgery: light – thermal – and electrical application – Light – thermal – and electrical application – Electrical therapeutic systems
Reexamination Certificate
2008-07-01
2008-07-01
Getzow, Scott M. (Department: 3762)
Surgery: light, thermal, and electrical application
Light, thermal, and electrical application
Electrical therapeutic systems
Reexamination Certificate
active
10478207
ABSTRACT:
A method of treating tumor tissue of an individual is provided. The method is effected by applying to cells of the tumor tissue electrical field pulses having a strength, a repetition frequency and a pulse width selected capable of inducing endocytosis mediated cell death thereby treating the tumor tissue.
REFERENCES:
patent: 6241701 (2001-06-01), Hofmann
J. Belechradek, Jr. et al. Electrochemotherapy of Spontaneous Mammary Tumours in Mice (1991).
Maurice Chazal, et al. Treatment of hapatic metastases of colorectal cancer by electrochemotherapy: An experimental study in the rat. (1998).
L. Frank Glass, et al. Bleomycin-Mediated Electrochemotherapy of Metastatic Melanoma. (1996).
L. Frank Glass, et al. Bleomycin-mediated electrochemotherapy of basal cell carcinoma. (1996).
R. Heller, et al. Effective treatment of B16 melanoma by direct delivery of bleomycin using electrochemotherapy. (1997).
Richard Heller, et al. Phase I/II Trial for the Treatment of Cutaneous and Subcutaneous Tumors Using Electrochemotherapy. (1995).
Richard Heller, et al. Treatment of Cutaneous and Subcutaneous Tumors with Electrochemotherapy Using Intralesional Bleomycin. (1998).
Mark J. Jaroszeski, et al. In vivo antitumor effects of electrochemotherapy in a hepatoma model. (1996).
Yoko Kubota, et al. Histological Evaluation of the Effects of Electropermeabilization after Administration of Bleomycin on Bladder Cancer in the Rat. (1998).
Yoko Kubota, et al. Successful Treatment of Metastatic Skin Lesions with Electrochemotherapy. (1998).
Yoko Kubota, et al. Electropermeabilization in bladder cancer chemotherapy. (1996).
LM Mir, et al. Effective treatment of cutaneous and subcutaneous malignant tumours by electrochemotherapy. (1998).
Yosef Rosemberg, et al. Incorporation of macromolecules into cells and vesicles b low electric fields: induction of endocytotic-like processes. (1997).
Gregor Sersa, et al. Anti-tumor effectiveness of electrochemotherapy with bleomycin is increased by TNF-α on SA-1 tumors in mice. (1997).
Gregor Sersa, et al. Antitumor Effectiveness of Electrochemotherapy withcis-diamminedichlorlplatinum (II) in Mice. (1995).
Mark J. Jaroszeski, et al. Electrochemotherapy, Electrogenetherapy, and Transdermal Drug Delivery.
Michael Belehradek, M.D.et al. Electrochemotherapy, a New Antitumor Treatment. (1993).
Micheline Hyacinthe, M.D., et al. Electrically Enhanced Drug Delivery for the Treatment of Soft Tissue Sarcoma. (1998).
M.J. Jaroszeski, et al. Treatment of hepatocellular carcinoma in a rat model using electrochemotherapy. (2000).
Shigeki Kuriyama, M.D. et al. Electrochemotherapy for Colorectal Cancer with Commonly Used chemotherapeutic Agents in a Mouse Model. (2000).
Gregory Sersa, et al. Electrochemotherapy with Cisplatin: Clinical Experience in Malignant Melanoma Patients. (1999).
G. Sersa, et al. Electrochemotherapy with Cisplatin: Potentiation of Local Cisplatin Antitumour Effectiveness by Application of Electric Pulses in Cancer Patients. (1998).
Sergio Rodriguez-Cuevas, et al. Electrochemotherapy in Primary and Metastatic Skin Tumors: Phase II Trial Using Intralesional Bleomycin. (2001).
M. Cemazar, et al. Electrochemotherapy of tumours resistant to cisplatin: a study in a murine tumour model. (2001).
M. Cemazar, et al. Electroporation of human microvascular endothelial cells: evidence for an anti-vascular mechanism of electrochemotherapy. (2000).
Akiko Horiuchi, et al. Enhancement of Antitumor Effect of Bleomycin By Low-Voltage In Vivo Electroporation: A Study of Human Uterine Leiomyosarcomas in Nude Mice. (2000).
Entin Igor
Keisari Yona
Korenstein Rafl
Rosemberg Yosef
Getzow Scott M.
Ramot At Tel Aviv University Ltd.
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