Chemistry: analytical and immunological testing – Including sample preparation – Liberation or purification of sample or separation of...
Patent
1997-07-02
2000-04-25
Soderquist, Arlen
Chemistry: analytical and immunological testing
Including sample preparation
Liberation or purification of sample or separation of...
436 94, 436180, 422100, 422 70, G01N 3300, G01N 2100
Patent
active
060543256
ABSTRACT:
The invention provides exemplary systems, methods, and apparatus for distinctly allocating liquids containing chemical compositions or compounds to known locations in an organized manner so that assays may be performed on the compositions, or so that the chemical compositions may be combined with other distinct chemical compositions or reagents prior to evaluation. In one exemplary embodiment, the invention provides a fluid transfer system which comprises a donor member having a plurality of separate regions. At least some of the regions contain at least one chemical composition, with each chemical composition being distinct from any other chemical composition in the donor member. An acceptor member is also provided and includes a plurality of defined locations which are each adapted to receive a liquid medium. A transfer mechanism is provided to systematically transfer at least some of the chemical compositions from the donor member regions to at least some of the acceptor member locations such that the locale of each transferred chemical composition within the acceptor member is known. Further, each of the acceptor member locations has a volume that is less than about 500 .mu.l. In this way, a large number of acceptor member locations may be provided within a single system to efficiently transfer, in parallel fashion, large numbers of chemical compositions from the donor member to the acceptor member where evaluation or further processing of the chemical compositions may proceed.
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Barrett Ronald W.
Binnie Alastair A.
Kedar Haim
Sugarman Jeffrey H.
Gibby Darin J.
Glaxo Wellcom Inc.
Soderquist Arlen
Stevens Lauren L.
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