Method and apparatus for tissue disaggregation

Details Method and apparatus for tissue disaggregation Method and apparatus for tissue disaggregation

1973-10-26

1976-03-02

Lake, Roy

Solid material comminution or disintegration

Processes

With application of fluid or lubricant material

23259, 24119911, B02C 1908, B01L 300

Patent

active

039413179

ABSTRACT:
A method of disaggregating tissue, particularly those containing relatively soft cells of body organs, to component cells, is disclosed as well as apparatus for carrying out the method which permits obtaining relatively large quantities of single cells or small groups of cells, the membrane and contents of which are structurally and chemically intact and not adversely affected by the disaggregation process.

REFERENCES:
patent: 1186598 (1915-06-01), Mueser
patent: 2561273 (1951-07-01), Hamilton
patent: 3421858 (1969-01-01), Quinn
patent: 3458139 (1969-07-01), Edebo
patent: 3556414 (1971-01-01), Eberly
patent: 3560162 (1971-02-01), Mittleman
patent: 3865551 (1975-02-01), Saiki et al.
Vaage, "A Mechanical Technique for Obtaining High Yields of Viable Dispersed Tumor Cells," Transplantion, Vol. 6, No. 1, Jan. 1968, pp. 137-139.

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