Surgery – Controlled release therapeutic device or system – Implanted dynamic device or system
Patent
1987-04-29
1991-06-25
Rosenbaum, C. Fred
Surgery
Controlled release therapeutic device or system
Implanted dynamic device or system
424 93, 514866, A61K 922, A01N 9300
Patent
active
050263650
ABSTRACT:
A unique method and apparatus for therapeutically treating immunological disorders and disease states which are characterized by the present of immunologically abnormal leukocytes in the body of the afflicted subject is provided. The apparatus and methodology utilized a sealed diffusion chamber which may be surgically implanted in-vivo or may be extracorporeally joined to the circulatory system of the afflicted subject. In either mode of use, the diffusion chamber utilizes immunologically normal leukocytes of various types and concentration which are able to provide cell functions and cellular secretory products which therapeutically counterbalance the effects of the immunological abnormality within the afflicted subject.
REFERENCES:
patent: 4352883 (1982-10-01), Lim
patent: 4353888 (1982-10-01), Sefton
patent: 4364385 (1982-12-01), Lossef
patent: 4391909 (1983-07-01), Lim
patent: 4686098 (1987-08-01), Kopchick et al.
Rossini et al., "Science", vol. 219, pp. 975-977, 2-25-83.
Sun et al., "Diabetes", vol. 26, No. 12, Dec. 1977.
Davis, K. C., Hayward, A., Ozturk, G., et al., Lymphocyte Transfusion in a Case of Acquired Immunodeficiency Syndrome, Lancet 1:599-600 (1983).
Petrakis, N. L.; Davis, M.; Lucia, S. P.: The In Vivo Differentiation of Human Leukocytes into Histiocytes, Fibroblasts and Fat Cells in Subcutaneous Diffusion Chambers, Blood 17: 109-118 (1961).
Greenberger, J. S.; Hassan, L. R.; Karpas, A.; France, D. S.; Moloney, W. C. Leucocyte Alkaline Phosphatase Elevation in Human Acute Leukaemia Derived Cell Lines Cultured in Diffusion Chambers, Scand. J. Haematol. 19: 242-254 (1977).
AIDS, Annals of the New York Academy of Sciences, vol. 437, pp. 312, 313, 326, 999, 1000, 1010, 1984.
Rossini et al., J. Clin. Invest. 74: 39-44 (1984).
Rossini et al., Ann. Rev. Immunol. 3:289-329 (1985).
Baratano et al., Diabetol. 19:255 (1980).
Zier et al., Diabetes 33:552 (1984).
Hunag & McClaren, Science 192:64 (1976).
Chappel et al., Metabolism 32 (Suppl. I):8 (1983).
Yale & Marliss, Clin. Exp. Immunol. 57:1-20 (1984).
Fauci et al., Ann. Int. Med. 102:800-813 (1985).
Fauci et al., Ann. Int. Med. 106:421-433 (1987).
Science 224:500-503 (1984).
Lane et al., N. Engl. J. Med. 311:1099-1103 (1984).
Carsten, A. L., Bibl. Haemat. 48:321-365 (1984).
Handler Eugene S.
Mordes John P.
Rossini Aldo A.
Rose Sharon
Rosenbaum C. Fred
The University of Massachusetts
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