Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals
Patent
1987-09-24
1992-08-04
Warden, Robert J.
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
436527, 436536, 436805, 422 8205, 422 8208, 422 8211, G01N 33536, G01N 33543
Patent
active
051358760
ABSTRACT:
A reusable biosensor is disclosed. A molecule containing a moiety of an antibody-antigen complex and photosensitive polymers are bonded to an optical conduit. When placed in a solution, the presence or absence of a second complementary moiety of an antibody-antigen complex can be determined by sensing whether or not the first moiety is complexed. The first moiety of an antibody-antigen complex can then be regenerated by transmitting light through the optical conduit which alters the structure of the photosensitive polymers to cause interference with said complex, thereby dissociating the second complementary moiety from the first moiety. The ability to regulate and control specific binding has applications can be useful in information storage devices, bioorganic electronic devices, and optical devices.
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Andrade Joseph D.
Herron James
Beisner William A.
University of Utah
Warden Robert J.
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