Method and apparatus for the measurement of analyte substances

Details Method and apparatus for the measurement of analyte substances Method and apparatus for the measurement of analyte substances

1989-02-17

1991-11-19

Lacey, David L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

436163, 204403, 204433, 422 56, G01N 33543

Patent

active

050665820

ABSTRACT:
A method for measuring trace amounts of analyte substance(s), which utilize a pH electrode is disclosed. This method is by far simpler than conventional optical detecting systems. The apparatus for practicing the method is also disclosed. By the use of pH electrode, the apparatus is compact, inexpensive and easy to operate, and hence usable in small-size and medium-size hospitals or clinical laboratories and by patient's bedside.

REFERENCES:
patent: 4318709 (1982-03-01), Falb
patent: 4713165 (1987-12-01), Conover
Chemical Abstracts, vol. 96, 1982 p. 96, abstract No. 155710n, Columbus, Ohio, U.S.; M. Mascini et al.: "pH Electrode-Based Enzyme Immunoassay for the Determination of Human Chorionic Gonadotropin" & Anal. Lett. 1982 15(B2), 101-113.
Chemical Abstracts, vol. 100, 1984, p. 270 abstract No. 153448k, Columbus, Ohio, U.S.; & JP-A-59 28 648 Kuraray Co. Ltd.) 15-02-84.
Chemical Abstracts, vol. 90, 1979, p. 244, abstract No. 164334w, Columbus, Ohio, U.S.; & JP-A-78 149 392 (Kuraray Co., Ltd.) 26-12-1978.
Chemical Abstracts, vol. 103, 1985, p. 394, abstract No. 209457u, Columbus, Ohio, U.S.; R. R. Premier et al.: "An Evaluation of the Use of a pH Indicator for the Detection of Beta-Lactamase in Enzyme Immunoassay", & J. Immunol. Methods 1985, 83(2) 371-377.
Boitieux, J-L, and Thomas, D; Clinical Biochemistry, 17, 151-156.

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