Surgery – Instruments – Light application
Reexamination Certificate
2002-03-04
2004-06-15
Cohen, Lee (Department: 3739)
Surgery
Instruments
Light application
C128S898000, C606S011000
Reexamination Certificate
active
06749602
ABSTRACT:
BACKGROUND OF THE INVENTION
1. Field of the Invention
This invention relates to laser apparatus and more particularly to laser apparatus for the treatment and/or removal of lesions and tattoos.
2. Prior Art
Pigmented lesions are common conditions of the skin of humans. Those lesions may be dermal lesions and include nevus of ota, nevus of ito, or epidermal lesions, including solar lentigenes, and freckles, liver or age spots, and birth marks.
Pigmented lesions include tattoos. These may be human caused tattoos and traumatic tattoos which are the result of an accident or mishap such as a scrape or an abrasion or the like where some foreign material becomes embedded under the skin. In each case, the skin becomes pigmented and scarred. The tattoos are made by dyes or inks which are deposited into the skin by a needle to create coloration and patterns on the skin of an individual. Tattoos are usually created by a vibrating needle by which colored pigments are introduced into the skin, usually to the papillary layer of the dermis. Tattoos may be green, blue, brown, black, bluegreen, aqua and red, yellow or orange. At some point in the lives of individuals having such lesions or tattoos, a decision is made in the attempt to remove those same colorations from their skin. Treatment of such pigmented lesions in the field of dermatology often involves a short pulse Q-Switched laser. Absorption of the energy of a short pulse from a Q-Switched laser effects a rapid heating and high pressure in the target tissue which is exposed to the laser radiation, resulting in an efficient breakup of that tissue structure. The disrupted structure begins to clear up by the normal immunological response. The tattoo is such a structure which is treated by means of the short pulse Q-Switched laser. Such lasers may include the ruby laser, the Alexandrite laser and the Nd:YAG laser.
Q-Switched Alexandrite lasers are commonly limited to an output of about one joule/pulse. The fluence required to treat a tattoo effectively then limits the area that can be treated from a single pulse to the order of about 3 mm diameter. Larger output is possible by the use of amplifier stages or by the use of large volume laser rods. These methods are complex and expensive and have limited commercial appeal.
The prior art such as found in U.S. Pat. No. 5,217,455 and 5,290,273, both issued to Oon T. Tan disclose Q-switched Alexandrite laser arrangements for the treatment of tattoos. Such treatment utilizes a single pulse of laser radiation to a chosen site, with multiple treatments applied over a period of weeks and/or months.
It is an object of the present invention to provide a method and apparatus for the treatment for pigmented lesions and tattoos which is an improvement over the prior art.
It is a further object of the present invention to provide a Q-Switched laser having improved output pulses and output energy for the treatment of lesions and tattoos than does the prior art.
It is still a further object of the present invention, to provide a Q-Switched laser which permits larger spot sizes at high repetition rate for treatment for lesions and tattoos than does the prior art.
It is still yet a further object of the present invention to provide a Q-Switched laser which minimizes the overall treatment time necessary for lesions and tattoos.
It is still yet a further object of the present invention to provide a Q-Switched laser arrangement which will minimize the number of treatments necessary for lesions and tattoos.
BRIEF SUMMARY OF THE INVENTION
The present invention involves a laser arrangement for the treatment of pigmented lesions or tattoos. In a typical treatment of a pigmented lesion or tattoo, the area of the lesion is irradiated with the laser. The laser output is characterized by short pulses of high peak power often in excess of 10 M watt. Immediately following a laser pulse, the area irradiated undergoes blanching caused by vaporization of tissue in the neighborhood of the pigment. A second laser pulse delivered to this area after vaporization would experience a great deal of scattering, thus preventing the laser light from reaching the intended target and consequently not being very effective at providing any further breakup of the pigmented structure. The time frame for the tissue vaporization to occur is or the order of 100 &mgr;s. If a second Q-Switched pulse is delivered to the pigmented lesion within that time interval, it would not experience the large scattering and therefore that second laser pulse can be very effective in treating that lesion.
It is common in the treatment of tattoos to increase the laser fluence as the lesion clears. The increase is needed since as the tattoo clears, there is less pigment to absorb the laser energy and, increased fluence (energy per unit area provided by a laser beam at a target site) is needed to insure that sufficient energy is absorbed by the pigment. If two pulses are delivered to the tissue in a window of less than about 100 &mgr;s, then the amount of pigment available to absorb the laser will be the same for both pulses.
A typical flashlamp excited solid state laser such as an Alexandrite laser uses a gain medium typically in the shape of a cylindrical rod. A flashlamp provides radiation needed to excite the rod, and a reflective chamber is used to insure that the radiation from the lamp reaches the laser rod. The radiation from the flashlamp excites the gain medium. Spontaneous radiation is emitted from the excited gain medium. Some of this radiation is reflected back into the gain medium by a pair of carefully aligned mirrors that form a resonator. This radiation experiences amplification as it traverses the gain medium. One of the mirrors is partially transmitting thus allowing a useful output from the laser. Stable laser oscillation begins when the round trip gain experienced by the radiation exactly balances the round trip losses, including the amount of radiation that exits the laser as useful output.
If a large loss is introduced in the laser resonator, the gain needed to achieve laser oscillation will be very large. A large amount of energy can be deposited in the laser rod achieving a large gain without laser oscillation taking place. If the losses are removed very rapidly while the gain in the medium is very high, the resulting laser will be well above threshold. The radiation in the resonator will grow very rapidly and a giant, short pulse will be developed and a portion of the energy previously deposited in the rod will be its output. This process is called “Q-Switching”.
The fraction of the energy stored in the rod that is extracted in a Q-Switched pulse depends on a number of factors including how much above threshold the laser is immediately after the losses are removed from the resonator, the energy resident in the rod at that time, and an inherent quantity of the gain medium commonly called the “saturation” fluence. This is the fluence that must be present in the resonator in order to extract a large fraction of the energy stored in the rod. The saturated fluence is the ratio of the emitted photon energy divided by the stimulated emission cross-section of the material. For the case of Alexandrite, the stimulated emission cross-section is very small, resulting in a large saturation fluence. As a result, in a common Alexandrite laser under flashlamp excitation, only a small fraction of the energy stored is extracted in the Q-Switch process. A significant fraction remains stored in the rod, If the resonator losses are restored, and the flashlamp excitation is extended past the time where the Q-Switch pulse was extracted, the stored energy in the rod will once again increase. Since a significant amount of energy is already present in the rod, the stored energy will reach a level equal to the level at which the first pulse was extracted with less energy from the flashlamp. That is, a second pulse whose energy is equal to that of the first may be extracted from the rod and will require less additional energy than the first one. The process may be c
Koschmann Eric Calvin
Sierra Rafael Armando
Zukeran Addison C.
Cohen Lee
Cynosure, Inc.
Halgren Don
Johnson Henry M
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