Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...
Patent
1997-03-07
1999-02-02
Kim, John
Liquid purification or separation
Processes
Liquid/liquid solvent or colloidal extraction or diffusing...
210483, 210488, 210489, 210490, 210491, 210496, 210503, 210504, 210506, 210508, 210767, 422 73, 422101, 422102, 436177, 436178, B01D 3700, B01D 6100
Patent
active
058660070
ABSTRACT:
The present invention provides a method and apparatus for separating a blood sample having a volume of up to about 20 milliliters into cellular and acellular fractions. The apparatus includes a housing divided by a fibrous filter into a blood sample collection chamber having a volume of at least about 1 milliliter and a serum sample collection chamber. The fibrous filter has a pore size of less than about 3 microns, and is coated with a mixture including between about 1-40 wt/vol % mannitol and between about 0.1-15 wt/vol % of plasma fraction protein (or an animal or vegetable equivalent thereof). The coating causes the cellular fraction to be trapped by the small pores, leaving the cellular fraction intact on the fibrous filter while the acellular fraction passes through the filter for collection in unaltered form from the serum sample collection chamber.
REFERENCES:
patent: 4678757 (1987-07-01), Rapkin et al.
patent: 5423989 (1995-06-01), Allen et al.
patent: 5665238 (1997-09-01), Whitson et al.
Clift Vaughan L.
Whitson Peggy A.
Barr Hardie R.
Kim John
The United States of America as represented by the Administrator
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