Chemistry: molecular biology and microbiology – Apparatus – Mutation or genetic engineering apparatus
Reexamination Certificate
2007-01-17
2011-12-13
Ketter, Jim (Department: 1636)
Chemistry: molecular biology and microbiology
Apparatus
Mutation or genetic engineering apparatus
C850S058000, C977S876000
Reexamination Certificate
active
08076124
ABSTRACT:
A method for the transient transformation of a living biological cell having an intact cell membrane defining an intracellular domain, and an apparatus for the transient transformation of biological cells. The method and apparatus include introducing a compartmentalized extracellular component fixedly attached to a cellular penetrant structure to the intracellular domain of the cell, wherein the cell is fixed in a predetermined location and wherein the component is expressed within in the cell while being retained within the compartment and wherein the compartment restricts the mobility and interactions of the component within the cell and prevents transference of the component to the cell.
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International Search Report and Written Opinion of the
McKnight Timothy E.
Melechko Anatoli V.
Simpson Michael L.
Ketter Jim
Scully , Scott, Murphy & Presser, P.C.
UT-Battelle LLC
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