Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...
Patent
1997-02-12
2000-05-02
Beisner, William H.
Chemistry: electrical and wave energy
Processes and products
Electrophoresis or electro-osmosis processes and electrolyte...
204452, 204453, 204601, 204603, 204604, 4352872, 435 6, 422 681, G01N 2726
Patent
active
060568593
ABSTRACT:
A method for staining immobilized nucleic acids includes the steps of affixing DNA probes to a solid substrate, moving target DNA material into proximity with the DNA probes, whereby the target DNA hybridized with specific ones of the DNA probes, and moving a fluorescent dye into proximity with the hybridized target DNA, whereby the fluorescent dye binds to the hybridized DNA to enable subsequent detection of fluorescence.
REFERENCES:
patent: 4908112 (1990-03-01), Pace
patent: 5073239 (1991-12-01), Hjerten
patent: 5092973 (1992-03-01), Zare et al.
patent: 5110431 (1992-05-01), Moring
patent: 5126022 (1992-06-01), Soan et al.
patent: 5132012 (1992-07-01), Miura et al.
patent: 5141621 (1992-08-01), Zare et al.
patent: 5180480 (1993-01-01), Manz
patent: 5250263 (1993-10-01), Manz
patent: 5296114 (1994-03-01), Manz
patent: 5376252 (1994-12-01), Ekstrom et al.
patent: 5585069 (1996-12-01), Zanzucchi et al.
patent: 5603351 (1997-02-01), Cherukuri et al.
patent: 5605662 (1997-02-01), Heller et al.
patent: 5632876 (1997-05-01), Zanzucchi et al.
patent: 5637469 (1997-06-01), Wilding et al.
patent: 5653939 (1997-08-01), Hollis et al.
patent: 5661028 (1997-08-01), Foote
patent: 5716825 (1998-02-01), Hancock et al.
patent: 5759779 (1998-06-01), Dehlinger
patent: 5804384 (1998-09-01), Muller et al.
patent: 5858195 (1999-01-01), Ramsey
Wilding et al., "Manipulation and Flow of Biological Fluids in Straight Channels Micromachined in Silicon", Clinical Chem., vol. 40, No. 1, 1994.
Wilding et al., "PCR in a Silicon Microstructure", Clinical Chemistry, vol. 40, No. 9, 1994.
Dasgupta et al., "Electroosmosis: A Reliable Fluid Propulsion System for Flow Injection Analysis", Analytical Chemistry, vol. 66, No. 11, Jun. 1, 1994.
Science .cndot. vol. 261 .cndot. Aug. 13, 1993 entitled: Micromachining a Miniaturized Capillary Electrophoresis-Based Chemical Analysis System on a Chip, by D. Jed Harrison, Karl Fluri, Kurt Seiler, Zhonghui Fan, Carlo S. Effenhauser, and Andreas Manz.
D. Jed Harrison, Andreas Manz, Zhonghui Fan, Hans Ludi, and H. Michael Widmer, "Capillary Electrophoresis and Sample Injections Systems Integrated on a Planar Glass Chip" Analytical Chemistry, vol. 64, No. 17 (Sep. 1, 1992) 1926-1932.
Carlo S. Effenhauser, Andreas Manz, and H. Michael Widmer, "Glass Chips for High Speed Capillary Electrophoresis Separations with Submicrometer Plate Heights" Analytical Chemistry, vol. 65, No. 19 (Oct. 1, 1993) 2637-2642.
M. Deml, F. Foret, and P. Bocek, "Electric Sample Splitter for Capillary Electrophoresis" Journal of Chromatography, 320 (1985) 159-165.
Foote Robert S.
Jacobson Stephen C.
Ramsey J. Michael
Beisner William H.
Lockheed Martin Energy Research Corporation
LandOfFree
Method and apparatus for staining immobilized nucleic acids does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and apparatus for staining immobilized nucleic acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and apparatus for staining immobilized nucleic acids will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1591369