Measuring and testing – Liquid analysis or analysis of the suspension of solids in a... – Content or effect of a constituent of a liquid mixture
Patent
1974-02-08
1976-11-02
Swisher, S. Clement
Measuring and testing
Liquid analysis or analysis of the suspension of solids in a...
Content or effect of a constituent of a liquid mixture
734256, B01D 1508
Patent
active
039889211
ABSTRACT:
According to the method disclosed, a capillary tube is first dipped into a sample receptacle and filled through capillary action. The tube is then withdrawn from the receptacle and lowered over a chromatographic plate such that the lower end of tube either just touches the plate or is spaced therefrom such that there is a small gap between the end of the tube and the plate. Air pressure is then applied to the other end of the capillary tube -- in the first instance to drive the liquid in the capillary out onto the plate at a known rate; in the second instance air pressure is applied to the other end of the capillary tube to form a droplet that bridges the gap between the tube end and the plate. Once the droplet makes contact with the plate, it is sucked into the interstices of the coating material of the plate. In alternative methods of the invention, air pressure is used to control the volume of the sample admitted to the capillary tube. A resilient, closed container, such as a bellows, is used for this purpose. This same container is positioned to be compressed as the tube is lowered for spotting to aid in forming the droplet and/or exhausting the tube at a reproducible rate.
An apparatus is also disclosed for performing the method of this invention. This apparatus includes a capillary tube and a drive means for raising and then lowering the filled tube with respect to the chromatographic plate for spotting the plate, then rotating the tube to a filling position having a sample receptacle and lowering the tube into and out of the receptacle whereby the tube is filled by capillary action. The drive means may either maintain a predetermined gap between the lower end of the tube and the chromatographic element or allow the tube to touch the plate. An adjustable pressure means supplies a fluid pressure to the other end of the tube.
REFERENCES:
patent: 3189413 (1965-06-01), Davis
patent: 3193358 (1965-07-01), Baruch
patent: 3495446 (1970-02-01), Williamson
patent: 3843323 (1974-10-01), Quame
Mortenson C. W.
Swisher S. Clement
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