Optics: measuring and testing – By shade or color – Fluid color transmission examination
Patent
1978-11-09
1980-12-23
Evans, F. L.
Optics: measuring and testing
By shade or color
Fluid color transmission examination
250526, 250227, 356246, 356440, 422102, 435291, 435808, G01N 2127
Patent
active
042407516
ABSTRACT:
A novel combination and a method are disclosed for detecting and measuring a predetermined substance capable of being specifically bound. The combination comprises a novel adapter which eliminates contact of a light conducting and receiving probe with the sample. The novel combination comprises (1) a fiber optic colorimeter comprising a light source, a means for detecting and measuring light, and a probe containing a plurality of optic fibers including a first light conducting means for conducting light from the light source of the colorimeter to a test sample and a second light conducting means for conducting light from the test sample to the means for detecting and measuring light and (2) a microplate having one or more wells, each of which is adapted to contain a liquid test sample, for use in a predetermined colorimetric medical diagnostic test, wherein a reflective surface is disposed below the bottom of the well of said microplate, said well is adapted to accommodate the probe of said fiber optic colorimeter, and wherein said probe includes an attachment means joinable in a close-fitting engagement with an upper portion of each well in said microplate, the attachment means not engaging said liquid sample. The method of the invention is especially suitable for rapid manual examination of sample wells in microplates.
REFERENCES:
patent: 3627432 (1971-12-01), Bergmann
patent: 3628872 (1971-12-01), Miranda
patent: 3654090 (1972-04-01), Schuurs et al.
patent: 3740155 (1973-06-01), Keller et al.
patent: 3791932 (1974-02-01), Schuurs et al.
patent: 3932763 (1976-01-01), Weinstein
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patent: 4075062 (1978-02-01), Shibata et al.
patent: 4152075 (1979-05-01), Rellstab et al.
Levine et al., IBM Technical Disclosure Bulletin, vol. 18, No. 11, Apr. 1976, pp. 3754-3756.
Linnecke Carl B.
Wong Daniel
Akzona Incorporated
Evans F. L.
Falk Robert H.
Wendel Charles A.
Young Francis W.
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