Surgery – Blood drawn and replaced or treated and returned to body – Constituent removed from blood and remainder returned to body
Patent
1981-05-04
1985-04-23
Howell, Kyle L.
Surgery
Blood drawn and replaced or treated and returned to body
Constituent removed from blood and remainder returned to body
604 6, A61M 103
Patent
active
045127638
ABSTRACT:
A method for removing a constituent such as immunoglobulins, lymphocytes, or immune complexes from a component of a patient's blood comprises the steps of: removing blood from the patient; separating the constituent containing component from the rest of the patient's blood; preparing an antibody; contacting the constituent containing component with the antibody so that the antibody may adsorb the constituent from the component; recombining the antibody contacted constituent containing component with the other components of the removed blood; and injecting the combined components of blood into the patient; wherein the adsorbing antibody is prepared by the steps of: removing selected cells from the constituent containing component of the patient's blood; injecting the removed cells into a non-human animal; allowing the non-human animal to manufacture antibodies to the injected cells; removing blood from the non-human animal; separating the same constituent containing component from the removed blood of the non-human animal; and removing the antibody from the constituent containing component of the non-human animal's blood. Another method for making the adsorbent antibody includes the steps of: creating cell cultures; cloning the antibody producing cells; removing large quantities of the antibody; and purifying the antibody. General and specific apparatus for effecting the above methods are also disclosed.
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patent: 3857393 (1974-12-01), Rose
patent: 3964467 (1976-06-01), Rose
patent: 4111199 (1978-09-01), Djerassi
patent: 4170056 (1979-10-01), Meyst et al.
patent: 4215688 (1980-08-01), Terman et al.
Gamma Medical Products, Inc.
Howell Kyle L.
Jaworski Francis J.
Oliveras R. Martin
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