Surgery – Instruments – Electrical application
Patent
1997-04-22
1998-09-15
Peffley, Michael
Surgery
Instruments
Electrical application
606 41, 604 22, 607101, 607102, A61B 1739
Patent
active
058073957
ABSTRACT:
A methods and apparatuses for ablation or hyperthermic treatment of body tissue are disclosed, wherein the application of radio-frequency ablative or hyperthermic energy is accompanied by the infusion of a conductive solution into the tissue, such that a virtual electrode is created. The virtual electrode results from the increased conductivity of the tissue in the area being treated due to the presence of conductive solution, such that the area of tissue being treated is enlarged as compared with non-fluid-assisted application of energy. In one embodiment, a catheter having a hollow helical electrode
eedle on the distal end thereof is provided, such that the electrode
eedle can be screwed into the tissue to be treated. A conductive fluid, such as saline, saturated saline, or Ringer's solution, is infused into the tissue to be treated via the hollow electrode and a lumen extending along the length of the catheter. In another embodiment of the invention, an implantable infusion port for fluid-assisted ablation and/or hyperthermia is provided with an elongate catheter having a hollow electrode
eedle on the distal end thereof. The port is subcutaneously implanted with the electrode
eedle situated within the tissue to be treated. A percutaneous needle facilitates the introduction of conductive fluid and/or chemotherapeutic agents into the tissue via a lumen in the catheter and the hollow electrode
eedle. The percutaneous needle also makes electrical contact with a conductor in the catheter, such that as fluid is being introduced into the tissue, radio-frequency energy may be applied to the tissue being treated.
REFERENCES:
patent: 4307720 (1981-12-01), Weber, Jr.
patent: 4506680 (1985-03-01), Stokes
patent: 4641649 (1987-02-01), Walinsky et al.
patent: 4674498 (1987-06-01), Stasz
patent: 4682596 (1987-07-01), Bales et al.
patent: 4748979 (1988-06-01), Hershenson
patent: 4802476 (1989-02-01), Norenberg et al.
patent: 4832048 (1989-05-01), Cohen
patent: 4850353 (1989-07-01), Stasz et al.
patent: 4862890 (1989-09-01), Stasz et al.
patent: 4869248 (1989-09-01), Narula
patent: 4896671 (1990-01-01), Cunningham et al.
patent: 4936281 (1990-06-01), Stasz
patent: 4966597 (1990-10-01), Cosman
patent: 4976711 (1990-12-01), Parins et al.
patent: 4977902 (1990-12-01), Sekino et al.
patent: 4979948 (1990-12-01), Geddes et al.
patent: 5056517 (1991-10-01), Fenici
patent: 5057107 (1991-10-01), Parins et al.
patent: 5078717 (1992-01-01), Parins et al.
patent: 5083565 (1992-01-01), Parins
patent: 5087256 (1992-02-01), Taylor et al.
patent: 5098431 (1992-03-01), Rydell
patent: 5122137 (1992-06-01), Lennox
patent: 5125928 (1992-06-01), Parins et al.
patent: 5129396 (1992-07-01), Rosen et al.
patent: 5150717 (1992-09-01), Rosen et al.
patent: 5171311 (1992-12-01), Rydell et al.
patent: 5178618 (1993-01-01), Kandarpa
patent: 5188635 (1993-02-01), RadtKe
patent: 5192280 (1993-03-01), Parins
patent: 5197963 (1993-03-01), Parins
patent: 5197964 (1993-03-01), Parins
patent: 5215103 (1993-06-01), Desai
patent: 5220927 (1993-06-01), Astrahan et al.
patent: 5234004 (1993-08-01), Hascoet et al.
patent: 5242442 (1993-09-01), Hirschfeld
patent: 5269781 (1993-12-01), Howell, III
patent: 5277201 (1994-01-01), Stern
patent: 5281217 (1994-01-01), Edwards et al.
patent: 5281218 (1994-01-01), Imran
patent: 5290286 (1994-03-01), Parins
patent: 5336222 (1994-08-01), Durgin, Jr. et al.
patent: 5342357 (1994-08-01), Nardella
patent: 5348554 (1994-09-01), Imran et al.
patent: 5370675 (1994-12-01), Edwards et al.
patent: 5385544 (1995-01-01), Edwards et al.
patent: 5403311 (1995-04-01), Abele et al.
patent: 5413588 (1995-05-01), Rudi e et al.
patent: 5415654 (1995-05-01), Daikuzono
patent: 5431649 (1995-07-01), Mulier et al.
patent: 5454807 (1995-10-01), Lennox et al.
patent: 5458597 (1995-10-01), Edwards et al.
patent: 5464437 (1995-11-01), Rei d et al.
patent: 5496271 (1996-03-01), Burton et al.
patent: 5505730 (1996-04-01), Edwards
patent: 5507743 (1996-04-01), Edwards et al.
patent: 5599294 (1997-02-01), Edwards et al.
"Differential Response of Normal and Tumor Microcirculation to Hyperthermia," by T. E. Dudar et al, Cancer Research, vol. 44, Feb. 1984, pp. 605-612.
"Progress in Hyperthermia?," by J. R. Oleson, Int. J. Radiation Oncology, Biology, Physics, vol. 20, (Feb. 1991), pp. 1143-1144.
"Percutaneous Transperineal Prostate Cryosurgery Using Transrectal Ultrasound Guidance: Animal Model," by G. Onik et al., Urology, vol. 37, No. 3, (Mar. 1991) p. 277.
"Physical and Dynamic Characteristics of DC Ablation in Relation to the Type of Energy Delivery and Catheter Design," by Robert Lemery et al., PACE, vol. 14, Jul. 1991, pp. 1158-1198.
"Basic and Clinical Studies of Local Hypothermia For Prostatic Cancer," by Masataka Hirai, Nippon Hinyokika Gakkai Zasshi, vol. 83, No. 5, May 1992, pp. 597-604.
"Interstitial Laser Hyperthermia," by A. Masters et al., Seminars in Surgical Oncology, vol. 8, (1992), pp. 242-249.
"Prediction of Treatment Temperatures in Clinical Hyperthermia of Locally Advanced Breast Carcinoma: The Use of Contrast Enhanced Computer Tomography," by H. Lyng et al., Int. J. Radiation Oncology, Biol. Phys., vol. 26, (Jan. 1993), pp. 451-457.
"Thermometry of Interstitial Hyperthermia Given as an Adjuvant to Brachytherapy for the Treatment of Carcinoma of the Prostate," by S. D. Prionas et al., Int. J. Radiation Oncology, Biol. Phys., vol. 28. (Sep. 1993), pp. 151-162.
"Transurethral Radio Frequency Thermomtherapy for Symptomatic Benign Proststic Hyperplasia," by A. Corica et al., Eur Urol, vol. 23, 1993, pp. 312-317.
"Benign Prostatic Hypertrophy Treatment by Transurethral Radiofrequency Hyperthermia with Thermex II," by J.L. Viguier et al., Eur Urol, vol. 23, 1993, pp. 318-321.
"Transurethral Thermotherapy of the Benign Prostate Hypertrophy Controlled by Radiometry," by G. Belot et al., Eur Urol, vol. 23, 1993, pp. 326-329.
"Transurethral Needle Ablation (TUNA) of the Prostate Using Low-Level Radiofrequency Energy: An Animal Experimental Study," by B. Goldwasser et al., Eur Urol, vol. 24, 1993, pp. 400-405.
"Needle Ablation Using Radio Frequency Current as a Treatment of Benign Prostatic Hyperplasia: Experimental Results in ex vivo Human Prostate," by J. Ramon et al., Eur Urol, vol. 24, 1993, pp. 406-410.
"Transurethral Needle Ablation (TUNA): Thermal Gradient Mapping and Comparison of Lesion Size in a Tissue Model and in Patients with Benign Prostatic Hyperplasia," by J.S. Rasor et al., Eur Urol, vol. 24, 1993, pp. 411-414.
"Transurethral Needle Ablation (TUNA): Safety, Feasibility, and Tolerance of a New Office Procedure for Treatment of Benign Prostatic Hyperplasia," by C.C. Schulman et al., Eur Urol, vol. 24, 1993, pp. 415-423.
"Cooled Tip Ablation Results in Increased Radiofrequency Power Delivery and Lesion Size," PACE, vol. 17, Apr. 1994, Part II, p. 782.
"Barriers to Drug Delivery in Solid Tumors," by R. K. Jain, Scientific American, vol. 271, No. 1, (Jul. 1994), pp. 58-65.
"Hyperthermia in Cancer Therapy: Where Are We Today and Where Are We Going?" by R. A. Steeves, Bull. NY Acad. Med. (U.S.) vol. 68, No. 2, Mar.-Apr., pp. 341-350.
Abstract 832 "Hydro-Ablation: A New Method for Trans-Catheter Radiofrequency Ablation," by S.W. Adler, et al., EUR.J.C.P.E., vol. 4, No. 2, Jun. 1994.
Abstract 165, "Comparison of Radiofrequency (RF) Versus Microwave (MW) Energy Catheter Ablation of the Bovine Ventricular Mycardium," by L..A. Pires, M.D. et al., PACE, vol. 17, Apr. 1994, Part II.
Abstract 166, "Developing and Testing a Feedback Control System for Microwave Ablation: In Vitro and In Vivo Results," by P.J. Wang, M.D. et al, PACE, vol. 17, Apr. 1994, Part II.
Abstract 168, "Laser and Radiofrequency Catheter Ablation of Ventricular Myocardium in Dogs: a Comparative Test," by S. Enders, M.D. et al, PACE, vol. 17, Apr. 1994, Part II.
Abstract 0872, "Radiofrequency Delivery Through an Endocardial Cooled Catheter Results in Increased Lesion Size," by R. Ruffy et al, University of Utah, Salt Lake City, UT.
Abstract 0873, "Porous Metal Tipped Catheter Produces Larger Radiofrequency Lesions Through Tip Cooling,
Hoey Michael F.
Mulier Peter M. J.
Forrest Peter
Medtronic Inc.
Patton Harold R.
Peffley Michael
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