Agitating – Stirrer within stationary mixing chamber – Rotatable stirrer
Reexamination Certificate
2006-03-07
2006-03-07
Soohoo, Tony G. (Department: 1723)
Agitating
Stirrer within stationary mixing chamber
Rotatable stirrer
C366S325200, C366S348000
Reexamination Certificate
active
07008101
ABSTRACT:
In a method for reproducible dissolution of a pharmaceutical product in a dissolution medium contained within a vessel, a flow regime characterized by high turbidity and low bulk movement of dissolution medium is induced within the vessel. Simultaneously, solid particles of the pharmaceutical product on a bottom portion of the vessel are mechanically dispersed. Induction of the flow regime and mechanical dispersion of solid particles may be accomplished by a brush body adapted to sweep a bottom portion of the vessel. The brush body is repeatably biased into contact with the bottom portion of the vessel, and caused to rotate in a controlled manner.
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Daniels Kent
Her Majesty the Queen in right of Canada as represented by the
Ogilvy Renault LLP
Soohoo Tony G.
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