Method and apparatus for removal of cells from bone marrow

Details Method and apparatus for removal of cells from bone marrow Method and apparatus for removal of cells from bone marrow

1985-10-09

1990-02-27

Jones, W. Gary

Liquid purification or separation

Processes

Using magnetic force

210222, 210223, 435 2, B03C 100, B03C 102

Patent

active

049043919

ABSTRACT:
An improved system for removing cells from bone marrow wherein the cells are bound by monoclonal antibodies conjugated to magnetic particles, the system comprising a chamber provided with inlets and outlets for flowing through the chamber a liquid sample containing the bone marrow and magnetic conjugated antibodies bound to the cells and a magnetic field source associated with the chamber wherein the improvement comprises a non-uniform magnetic field in an ascending gradient from the inlet to the outlet.

REFERENCES:
patent: 4508625 (1985-04-01), Graham
Treleaven et al; "Removal of Neuroblastoma Cells . . . " The Lancet, 1/14/84, pp. 70-73.

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