Chemistry: electrical and wave energy – Processes and products – Electrophoresis or electro-osmosis processes and electrolyte...
Patent
1996-12-13
1998-11-10
Gorgos, Kathryn L.
Chemistry: electrical and wave energy
Processes and products
Electrophoresis or electro-osmosis processes and electrolyte...
204451, 204601, 204603, G01N 2726, G01N 27447
Patent
active
058338268
ABSTRACT:
An electrophoresis system including means for reducing the distortion of a sample zone eluting from a capillary electrophoresis separation capillary is disclosed. The system includes one or more separation capillaries, each separation capillary having an inlet end and an outlet end; a first electrode in electrical communication with the inlet ends of the separation capillaries; a second electrode in electrical communication with the outlet ends of the separation capillaries; and one or more focusing electrodes in electrical communication with the outlet ends of the separation capillaries. In operation, the voltage of each of the electrodes is adjusted such that (i) the sample zone is transported from the inlet end to the outlet end of the separation capillaries and (ii) the distortion of the sample zone eluting from the separation capillaries is reduced.
REFERENCES:
patent: 5073239 (1991-12-01), Hjerten
patent: 5141609 (1992-08-01), Sweedler et al.
patent: 5439578 (1995-08-01), Dovichi et al.
patent: 5529679 (1996-06-01), Takahashi et al.
Gorgos Kathryn L.
Grossman Paul D.
Starsiak Jr. John S.
The Perkin-Elmer Corporation
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