Method and apparatus for rapid mixing of small volumes for enhan

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...

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210222, 366219, 366241, 435 724, 435 725, 435 30, 4352872, 436526, 436548, 436808, C12Q 124, G01N 33543

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active

054686164

ABSTRACT:
A method and apparatus for accelerating at least one definitive biological reaction including increasing the accuracy of determinations made therefrom. The reaction involves selected viable biological cells which are prepared in a small sample volume and rapidly mixed with microspheres having antibody specific at least to specific ones of the cells bound thereto. The microspheres can be magnetic and the bound cells can be magnetically removed to analyze the remaining blood cell populations. The microspheres can be introduced sequentially or simultaneously.

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Cotter et al, Journ. Immunol. 127, 1355-1360, 1981.
Brazenor et al, Jour. Immunol. Methods., 2, 325-328, 1973.

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