Method and apparatus for production of spin-polarized medical-gr

Refrigeration – Cryogenic treatment of gas or gas mixture – Separation of gas mixture

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62 555, 62919, 62925, 1286534, 20415722, F25J 100

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active

059341033

ABSTRACT:
Spin-polarized xenon gas is provided in medical-grade purity for use as a contrast medium in MRI studies by use of collision-induced transfer of spin energy to the xenon gas from laser-pumped spin-polarized Rb gas. The Rb gas is provided by thermally vaporizing solid Rb at low pressure in a container having an inside surface coated with a siliconizing agent and exposed to the Rb gas. The combined xenon and Rb gases are separated after transfer of the spin energy in order to provide a sufficient purity of the xenon gas by use of a cryogenic separation process. The Rb gas is removed from the xenon gas and is returned cryogenically to a solid stated to an acceptable level of purity for the xenon gas. The gas may be analyzed optically to measure the remaining Rb concentration.

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patent: 4724117 (1988-02-01), Stearns et al.
patent: 5617860 (1997-04-01), Chupp et al.
patent: 5642625 (1997-07-01), Cates, jr. et al.

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