Method and apparatus for producing position addressable combinat

Details Method and apparatus for producing position addressable combinat Method and apparatus for producing position addressable combinat

1996-07-24

1998-06-09

Hutzell, Paula K.

Chemistry: molecular biology and microbiology

Apparatus

Including measuring or testing

530333, 530334, 435 6, 435 71, 436518, 436527, 536 253, C12M 100

Patent

active

057632634

ABSTRACT:
Method and apparatus for producing combinatorial position-addressable libraries of different-sequence oligomers or different-substituent small molecule compounds are disclosed. The method employs massive parallel synthesis by stepwise subunit addition or substituent addition in a dense capillary-tube array. The libraries allow high throughput screening of library compounds in either solid phase or solution phase, and position-related identification of active library compounds.

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