Chemistry: molecular biology and microbiology – Apparatus – Bioreactor
Patent
1985-04-15
1987-07-14
Scott, Samuel
Chemistry: molecular biology and microbiology
Apparatus
Bioreactor
423237, C12M 120
Patent
active
046802690
ABSTRACT:
This invention relates to a porous barrier impregnated with an acidic compound positioned in overlying relation atop the biochemical test wells portion of an antibiotic microtiter test plate effective to intercept and neutralize volatile alkaline products evolved through bacterial growth taking place therein before they can diffuse and contaminate nearby test wells and produce erroneous pH-sensitive color tests. The invention also relates to an improved method for preventing cross-contamination of the biochemical tests being carried out in test wells adjacent microtiter test wells, the contents of which are being analyzed for antibacterial activity, which consists of covering the biochemical test wells with a porous medium impregnated with an acidic compound capable of neutralizing gaseous alkaline products resulting from bacterial growth in wells containing sub-inhibitory antibiotic levels thereby protecting the biochemical tests from erroneous pH-sensitive indicator color changes.
REFERENCES:
patent: 3438737 (1969-04-01), Atkinson et al.
patent: 3873269 (1975-03-01), Kraffczyk et al.
patent: 4070300 (1978-01-01), Moroni et al.
patent: 4080423 (1978-03-01), Smith et al.
Kamen Noah
Pasco Laboratories, Inc.
Scott Samuel
Spangler, Jr. Edwin L.
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