Method and apparatus for preserving biological materials

Details Method and apparatus for preserving biological materials Method and apparatus for preserving biological materials

1976-04-07

1977-06-21

Capossela, Ronald C.

Refrigeration

Processes

Treating an article

62 78, 62514R, 128 1R, 195 18, F25D 1304

Patent

active

040303144

ABSTRACT:
Preservation of biological materials is accomplished by apparatus and a process with and by which the material is cooled at a substantially linear rate to approximately freezing temperature, changed from the liquid to the solid phase at relatively constant temperature, and cooled at a substantially linear rate to an end temperature. The environment surrounding the material is rapidly chilled when the material reaches freezing temperature or a temperature minimally warmer than freezing temperature in the liquid phase to initiate phase change with minimal risk of super cooling the material, and is then warmed to freezing temperature or a temperature minimally cooler than freezing temperature to minimize temperature drop in the material upon completion of phase change. The apparatus contemplates, among other things, preselection of cooling rates, duration of phase change, and the end temperature.

REFERENCES:
patent: 2655007 (1953-10-01), Lazar
patent: 3092974 (1963-06-01), Haumann et al.
patent: 3940943 (1976-03-01), Sikes et al.

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