Method and apparatus for prediction of cardiac electrical instab

Details Method and apparatus for prediction of cardiac electrical instab Method and apparatus for prediction of cardiac electrical instab

1995-05-26

1996-10-01

Kamm, William E.

Surgery

Truss

Pad

A61B 5468

Patent

active

055603700

ABSTRACT:
A method and apparatus for predicting cardiac electrical instability simultaneously assesses T-Wave Alternans and QT Interval Dispersion. T-wave alternation is an excellent predictor of cardiac electrical instability but can be influenced by mechano-electrical coupling. Thus, a measure of alternation has a high degree of sensitivity but a low degree of specificity. The low specificity of alternation is addressed by simultaneously analyzing QT interval dispersion. Dispersion is not a measure of excitable stimulus and is not sensitive to mechano-electrical coupling. The resulting combination of alternans and dispersion yields an accurate predictor of cardiac electrical instability caused by intrinsic factors.

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Surawicz, B., "ST-Segment, T-Wave, and U-Wave Changes During Myocardial Ischemia and After Myocardial Infarction", Canadian Journal of Cardiology, Suppl. A:71A-84A, Jul., 1986, extract only.

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