Method and apparatus for predicting acute response to...

Surgery – Diagnostic testing – Cardiovascular

Reexamination Certificate

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Reexamination Certificate

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10780794

ABSTRACT:
A method and apparatus for predicting acute response to cardiac resynchronization therapy is disclosed. The method can comprise measuring a first interval during an intrinsic systolic cycle and measuring a second interval during a stimulated systolic cycle. The acute response can be predicted by comparing the percent change in duration between the first interval and the second interval against a pre-determined threshold value. The first and second time intervals can be measured using, for example, a surface ECG or, alternatively, an intracardiac electrogram. In one embodiment, the first interval can be the duration of an intrinsic QRS complex measured during a non-stimulated systolic cycle. Similarly, the second interval can be the duration of a stimulated QRS complex measured during a stimulated systolic cycle.

REFERENCES:
patent: 5469858 (1995-11-01), Osborne
patent: 5694942 (1997-12-01), Escalona
patent: 5827196 (1998-10-01), Yeo et al.
patent: 6144880 (2000-11-01), Ding et al.
patent: 2002/0143264 (2002-10-01), Ding et al.

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