Radiant energy – Photocells; circuits and apparatus – Optical or pre-photocell system
Reexamination Certificate
2006-02-01
2010-02-16
Sohn, Seung C (Department: 2878)
Radiant energy
Photocells; circuits and apparatus
Optical or pre-photocell system
C356S073000, C422S064000, C436S045000
Reexamination Certificate
active
07663092
ABSTRACT:
A phase contrast quadrature interferometric method and apparatus for determining the presence or absence of a target analyte in a sample. The method includes probing a substrate exposed to the sample with a laser beam. The substrate includes a reflecting surface with a first region having recognition molecules specific to the target analyte and a second region without recognition molecules. The method also includes probing the first and second region, and measuring time dependent intensity on a photodetector at one or both of a pair of quadrature angles of a reflected diffraction signal. The apparatus includes a laser source, a platform for receiving the planar array, an objective lens offset from the platform by approximately a focal length, and a split photodetector means for measuring a first quadrature and a second quadrature in a signal resulting from reflection of the laser beam.
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Nolte David D.
Peng Leilei
Regnier Fred E.
Zhao Ming
Bose McKinney & Evans LLP
Purdue Research Foundation
Sohn Seung C
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