Data processing: measuring – calibrating – or testing – Measurement system in a specific environment – Mechanical measurement system
Patent
1996-12-31
1999-11-23
Wachsman, Hal Dodge
Data processing: measuring, calibrating, or testing
Measurement system in a specific environment
Mechanical measurement system
702 45, 702 76, 382107, 382131, 356 285, 600425, 600441, 600453, G01P 336
Patent
active
059916974
ABSTRACT:
Optical Doppler tomography permits imaging of fluid flow velocity in highly scattering media. The tomography system combines Doppler velocimetry with high spatial resolution of partially coherent optical interferometry to measure fluid flow velocity at discrete spatial locations. Noninvasive in vivo imaging of blood flow dynamics and tissue structures with high spatial resolutions of the order of 2 to 10 microns is achieved in biological systems. The backscattered interference signals derived from the interferometer may be analyzed either through power spectrum determination to obtain the position and velocity of each particle in the fluid flow sample at each pixel, or the interference spectral density may be analyzed at each frequency in the spectrum to obtain the positions and velocities of the particles in a cross-section to which the interference spectral density corresponds. The realized resolutions of optical Doppler tomography allows noninvasive in vivo imaging of both blood microcirculation and tissue structure surrounding the vessel which has significance for biomedical research and clinical applications.
REFERENCES:
patent: 5501226 (1996-03-01), Petersen et al.
patent: 5551434 (1996-09-01), Iinuma
patent: 5587785 (1996-12-01), Kato et al.
Bail et al, "Optical Coherence Tomography With the `Spectral Radar` Fast Optical Analysis in Volume Scatters By Short Coherence Interferometry" (No Date).
Chen et al., "Optical Doppler tomography: Imaging in vivo Blood Flow Dynamics Following Pharmacological Intervention and Photodynamic Therapy" (1997) pp. 1-20 (Jul. 1997).
Gusmeroli et al., "Distributed laser Doppler velocimeter" (1991) Optics Letters vol. 16 No. 17 pp. 1358-1360 (Jun. 1991).
Barton et al., "Optical Low-Coherence Reflectometry to Enhance Monte Carlo Modeling of Skin" (1997) Journal of Biomedical Optics vol. 2 No. 2 pp. 226-234 (Apr. 1997).
Huang et al., "Optical Coherence Tomography" (1991) Science, vol. 254, pp. 1178-1181 (Nov. 1991).
Chen et al., "Optical Doppler tomographic imaging of fluid flow velocity in highly scattering media" (1997) Optics Letters, vol. 22, No. 1, pp. 64-66 (Jan. 1997).
Chen, et al., "Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography" (1997) Optics Letters, vol. 22, No. 14, pp. 1119-1121, (Jul. 1997).
Wang et al., "Characterization of fluid flow velocity by optical Doppler tomography" (1995) Optics Letters, vol. 20, No. 11, pp. 1337-1339, (Jun. 1995).
Chen Zhongping
Milner Thomas Edward
Nelson John Stuart
Dawes Daniel L.
The Regents of the University of California
Wachsman Hal Dodge
LandOfFree
Method and apparatus for optical Doppler tomographic imaging of does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and apparatus for optical Doppler tomographic imaging of , we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and apparatus for optical Doppler tomographic imaging of will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1233890