Surgery – Diagnostic testing – Liquid collection
Patent
1997-02-07
1999-06-22
Hindenburg, Max
Surgery
Diagnostic testing
Liquid collection
604 22, 604290, A61B 500
Patent
active
059138335
ABSTRACT:
This invention provides a method and apparatus for disrupting the outermost layer of skin, the stratum corneum, to provide access to biological fluid, which can then be used to determine the concentration of glucose in blood. The invention can be used to extract interstitial fluid, blood, and mixtures of interstitial fluid and blood from the body of a human or an animal.
The method comprises the steps of (1) attaching a receptacle for collecting biological fluid to the surface of the skin of a patient, (2) introducing an oscillation concentrator attached to an oscillation element into the receptacle, (3) positioning the oscillation concentrator at a desired distance from the surface of the skin, (4) activating the oscillation element to transversely oscillate the attached oscillation concentrator, (5) collecting the biological fluid after a specific period of time, and (6) analyzing the biological fluid for the presence of an analyte.
REFERENCES:
patent: 4708127 (1987-11-01), Abdelghani
patent: 4767402 (1988-08-01), Kost et al.
patent: 4780212 (1988-10-01), Kost et al.
patent: 4787888 (1988-11-01), Fox
patent: 4821740 (1989-04-01), Tachibana et al.
patent: 4948587 (1990-08-01), Kost et al.
patent: 4953565 (1990-09-01), Tachibana et al.
patent: 5007438 (1991-04-01), Tachibana et al.
patent: 5016615 (1991-05-01), Driller et al.
patent: 5076208 (1991-12-01), Zohar et al.
patent: 5115805 (1992-05-01), Bommannan et al.
patent: 5147291 (1992-09-01), Cukier
patent: 5171215 (1992-12-01), Flanagan
patent: 5222937 (1993-06-01), Kagawa
patent: 5231975 (1993-08-01), Bommannan et al.
patent: 5267985 (1993-12-01), Shimada et al.
patent: 5323769 (1994-06-01), Bommannan et al.
patent: 5405614 (1995-04-01), D'Angelo et al.
patent: 5415629 (1995-05-01), Henley
patent: 5421816 (1995-06-01), Lipkovker
patent: 5437606 (1995-08-01), Tsukamoto
patent: 5445611 (1995-08-01), Eppstein et al.
patent: 5458140 (1995-10-01), Eppstein et al.
Brown, L. and Langer, R.; "Transdermal Delivery of Drugs", Ann. Rev. Med., vol. 39, pp. 221-229 (1988).
ter Haar, G. R. and Daniels, S.; "Evidence for ultrasonically induced cavitation in vivo", Phys. Med. Biol., vol. 26, NO. 6, pp. 1145-1149 (1981).
Levy, D. et al; "Effect of Ultrasound on Transdermal Drug Delivery to Rats and Guinea Pigs", J. Clin. Invest., vol. 83, pp. 2074-2078 (Jun. 1989).
Elstrom Tuan A.
Shain Eric B.
Abbott Laboratories
Hindenburg Max
Weinstein David L.
LandOfFree
Method and apparatus for obtaining biological fluids does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method and apparatus for obtaining biological fluids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method and apparatus for obtaining biological fluids will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1705011