Method and apparatus for observing three-dimensional...

Image analysis – Applications – Biomedical applications

Reexamination Certificate

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C382S154000, C435S359000

Reexamination Certificate

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10377671

ABSTRACT:
In order to make observation of localizations of in vivo expressed genes possible in an entire individual living organism such as animals, and plants, a living genetic recombinant specimen containing a marker that can be detected at the time when specific genes are expressed is sequentially severed, sectional images each of which corresponds to an image of sections severed are photographed in every scissions of the living specimen, and three-dimensional observation of the living specimen is implemented on the basis of the images photographed in every scissions described above, whereby three-dimensional localizations of expressed genes are observed in the living specimen.

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Translation of Notification of Reasons for Rejection from Japan Patent Office for Patent Application No. 2002-057935, Mar. 2005 (Japanese text also attached).
“Green Mice and Their Potential Usage in Biological Research” Ikawa et al. FEBS Letters 430 (1998) pp. 83-87.

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